Polynaphthalene sulphonate

Polynaphthalene sulphonate Uses, Dosage, Side Effects, Food Interaction and all others data.

Polynaphthalene sulphonate is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of HIV infection and other sexually transmitted diseases. This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people.

Table Of contents

• Polynaphthalene sulphonate
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Polynaphthalene sulphonate
Generic	PRO 2000
PRO 2000 Other Names	Polynaphthalene sulphonate
Type
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection.

How Polynaphthalene sulphonate works

Polynaphthalene sulphonate, also known as Polynaphthalene sulphonate/5, is a type of medicine called a microbicide. Microbicides are substances that protect the body from infection by microorganisms such as bacteria, viruses, and fungi. Microbicides work by either destroying the microbes or preventing them from establishing an infection.

Polynaphthalene sulphonate is a candidate topical microbicide for the prevention of sexually transmitted infections including infection by the Human Immunodeficiency Virus (HIV), the cause of Acquired Immunodeficiency Syndrome (AIDS). The compound is believed to block the entry of sexually transmitted disease (STD) pathogens into human cells. In addition to its demonstrated activity against HIV infection in laboratory tests and animal models, Polynaphthalene sulphonate has been shown to be active against other STD pathogens such as herpes, chlamydia, and the bacterium that causes gonorrhea. Designed to be applied vaginally prior to sexual intercourse, Polynaphthalene sulphonate promises to offer a discreet "safer sex" option that can be controlled by women.

Innovators Monograph

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