Polystyrene Sulfonate

Polystyrene Sulfonate Uses, Dosage, Side Effects, Food Interaction and all others data.

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.

Polystyrene sulfonate affects the exchange of sodium and potassium in the body. Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. It is a potassium-binding ion-exchange resin that can be administered orally (25 grams in 20% sorbitol) or rectally (50 grams in 20% sorbitol).

Trade Name Polystyrene Sulfonate
Generic Tolevamer
Tolevamer Other Names Polystyrene sulfonate, Polystyrene sulfonic acid, polystyrenesulfonic acid, Tolevamer
Type
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Polystyrene Sulfonate
Polystyrene Sulfonate

Uses

Polystyrene Sulfonate is a potassium-binding resin used in the treatment of hyperkalemia.

Used to treat abnormally high potassium levels.

Polystyrene Sulfonate is also used to associated treatment for these conditions: Hyperkalemia

How Polystyrene Sulfonate works

Polystyrene sulfonate, which is not absorbed, binds excess potassium, carrying it out of the body. The indigestible potassium polystryene sulfonate complex is excreted with the faeces, preventing the absorption of potassium into the blood stream. Hence, the serum potassium level decreases.

Toxicity

Overdose symptoms may include confusion, irritability, trouble thinking or concentrating, muscle weakness, or trouble breathing.

Food Interaction

  • Avoid multivalent ions.
  • Take on an empty stomach.

Elimination Route

Not absorbed following oral administration.

Half Life

none

Elimination Route

Feces.

Innovators Monograph

You find simplified version here Polystyrene Sulfonate

*** Taking medicines without doctor's advice can cause long-term problems.
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