Polystyrene Sulfonate
Polystyrene Sulfonate Uses, Dosage, Side Effects, Food Interaction and all others data.
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Polystyrene sulfonate affects the exchange of sodium and potassium in the body. Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. It is a potassium-binding ion-exchange resin that can be administered orally (25 grams in 20% sorbitol) or rectally (50 grams in 20% sorbitol).
Trade Name | Polystyrene Sulfonate |
Generic | Tolevamer |
Tolevamer Other Names | Polystyrene sulfonate, Polystyrene sulfonic acid, polystyrenesulfonic acid, Tolevamer |
Type | |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Polystyrene Sulfonate is a potassium-binding resin used in the treatment of hyperkalemia.
Used to treat abnormally high potassium levels.
Polystyrene Sulfonate is also used to associated treatment for these conditions: Hyperkalemia
How Polystyrene Sulfonate works
Polystyrene sulfonate, which is not absorbed, binds excess potassium, carrying it out of the body. The indigestible potassium polystryene sulfonate complex is excreted with the faeces, preventing the absorption of potassium into the blood stream. Hence, the serum potassium level decreases.
Toxicity
Overdose symptoms may include confusion, irritability, trouble thinking or concentrating, muscle weakness, or trouble breathing.
Food Interaction
- Avoid multivalent ions.
- Take on an empty stomach.
Elimination Route
Not absorbed following oral administration.
Half Life
none
Elimination Route
Feces.
Innovators Monograph
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