Praticef
Praticef Uses, Dosage, Side Effects, Food Interaction and all others data.
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Praticef is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Trade Name | Praticef |
Availability | Discontinued |
Generic | Cefonicid |
Cefonicid Other Names | Cefonicid, Cefonicido, Cefonicidum |
Related Drugs | amoxicillin, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin, Augmentin |
Type | |
Formula | C18H18N6O8S3 |
Weight | Average: 542.566 Monoisotopic: 542.034823652 |
Protein binding | 98% bound to plasma proteins. |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of bacterial infections caused by susceptible microorganisms.
How Praticef works
Praticef, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
Praticef Hypertension interaction
[Moderate] Parenteral cefonicid sodium contains approximately 85 mg (3.7 mEq) of sodium per each gram of cefonicid activity.
The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention.
Praticef Drug Interaction
Unknown: acetaminophen, acetaminophen, aspirin, aspirin, alprazolam, alprazolam, pseudoephedrine / triprolidine, pseudoephedrine / triprolidine, carboplatin, carboplatin, clotrimazole, clotrimazole
Praticef Disease Interaction
Major: colitisModerate: renal dysfunction, sodium, liver disease
Half Life
4.5 hours
Innovators Monograph
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