Procaina Serra

Procaina Serra Uses, Dosage, Side Effects, Food Interaction and all others data.

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaina Serra has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients .

Procaina Serra is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Procaina Serra (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine. Procaina Serra is an ester anesthetic. It is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-aminobenzoic acid (PABA), which is then excreted by the kidneys into the urine.

Procaina Serra
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Uses during Pregnancy
Uses during Breastfeeding
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Trade Name	Procaina Serra
Availability	Discontinued
Generic	Procaine
Procaine Other Names	Novocaine, Procaina, Procaine, Procainum, Vitamin H3
Related Drugs	lidocaine ophthalmic, cocaine nasal, bupivacaine
Type
Formula	C₁₃H₂₀N₂O₂
Weight	Average: 236.3101 Monoisotopic: 236.152477894
Groups	Approved, Investigational, Vet approved
Therapeutic Class
Manufacturer
Available Country	Spain
Last Updated:	September 19, 2023 at 7:00 am

Uses

Procaina Serra is a local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.

Used as a local anesthetic primarily in oral surgery

Procaina Serra is also used to associated treatment for these conditions: Otalgia

How Procaina Serra works

Procaina Serra acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Procaina Serra has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex.