Proctofoam Ns
Proctofoam Ns Uses, Dosage, Side Effects, Food Interaction and all others data.
Proctofoam Ns (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Proctofoam Ns is available by itself and in combination with other medications in various topical preparations. It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation.
Proctofoam Ns temporarily relieves pain, pruritis, burning and discomfort associated with minor lip and skin irritations and hemorrhoid's by inhibiting voltage gated sodium channels on neurons.
| Trade Name | Proctofoam Ns |
| Generic | Pramocaine |
| Pramocaine Other Names | Pramocaína, Pramocaine, Pramoxine |
| Weight | 1%, 1%, 1%, 1%, 1%, 1%, 1% |
| Type | Rectal foam, topical cream, topical gel, topical lotion, topical pad, topical spray, topical stick |
| Formula | C17H27NO3 |
| Weight | Average: 293.407 Monoisotopic: 293.199093733 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Proctofoam Ns is a local anesthetic and antipruritic agent found in various topical preparations.
It is indicated for temporary relief of pain and pruritus from minor lip and skin irritations as well as for temporary relief from pain, burning, itching and discomfort associated with hemorrhoids and other anorectal/anogenital disorders.
Proctofoam Ns is also used to associated treatment for these conditions: Dermatosis, Hemorrhoids, Itching of the perianal area, Skin Irritation
How Proctofoam Ns works
Proctofoam Ns reversibly binds and inhibits voltage gated sodium channels on neurons decreasing sodium permeability into the cell. This stabilizes the membrane and prevents ionic fluctuations needed for depolarization stopping any action potential propagation.
Toxicity
LD50 Mouse ip 300 mg/kg, LD50 Mouse sc 750 mg/kg
Food Interaction
No interactions found.Elimination Route
There is minimal absorption after topical administration and it is not given orally.
Innovators Monograph
You find simplified version here Proctofoam Ns
FAQ
What is Proctofoam Ns use for?
Proctofoam Ns is used to decrease swelling, itching and pain that is caused by minor skin irritations or hemorrhoids.It also used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders.
How safe Proctofoam Ns is?
Proctofoam Ns is a safe, steroid-free, itch-relieving option that can be used as needed.
What are the common side effects of Proctofoam Ns?
Proctofoam Ns may cause side effects include:
- redness, irritation, swelling, burning, stinging, or pain at affected area.
- dryness at affected area.
How long can I use Proctofoam Ns?
Do not use Proctofoam Ns for more than 14 days. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.Do not use your medicine more often than directed.
Is Proctofoam Ns safe for pregnancy?
Proctofoam Ns topical should only be given during pregnancy when benefits outweigh risks Proctofoam Ns topical has not been formally assigned to a pregnancy category by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy.
Can I take Proctofoam Ns with alcohol?
You should avoid alcohol while you're taking Proctofoam Ns. You should continue to avoid alcohol for 48 hours after you stop taking medication.
Is Proctofoam Ns safe for babies?
Proctofoam Ns may safe younger than 2 years baby .Do not use Proctofoam Ns for skin irritation in children younger than 2 years unless directed by the doctor.
How long does it take for Proctofoam Ns to work?
Clinical studies have shown that Proctofoam Ns hydrochloride begins working in as little as two minutes, and its effects last for up to eight hours.
How many times a day can I use Proctofoam Ns cream?
Proctofoam Ns cream/ointment use once or twice a day. It must not be applied more often than twice a day, and once a day is often sufficient.
Can i use Proctofoam Ns on my face?
Proctofoam Ns can be used to help relieve itching on the face and body.
How long can I use Proctofoam Ns?
You should not use for more than 14 days.
How does Proctofoam Ns work?
It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation.Proctofoam Ns is available by itself and in combination with other medications in various topical preparations.
Is Proctofoam Ns an anti inflammatory?
Proctofoam Ns is a topical aerosol foam containing a corticosteroid used as an anti-inflammatory/anti-itch agent and a local anesthetic used to relieve inflammatory and itching manifestations of corticosteroid-responsive skin conditions .
Is Proctofoam Ns good for hemorrhoids?
Proctofoam Ns is an anesthetic, or numbing medicine. Proctofoam Ns is used to treat pain or itching caused by insect bites, minor burns or scrapes, hemorrhoids, vaginal irritation, and minor skin rash, dryness, or itching.
Does Proctofoam Ns stop itching?
Topical treatments that contain hydrochloride can be applied directly to the source of the itch and can, therefore, work to relieve the itch quickly.
Is Proctofoam Ns a vasoconstrictor?
There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.
How does Proctofoam Ns work?
Proctofoam Ns is a drug that aids the body's mucus-clearing processes in the respiratory tract. It is used to relieve chest congestion. This medicine works by blocking a certain natural substance (known as histamine) that your body makes during an allergic reaction.
