Propethonum
Propethonum Uses, Dosage, Side Effects, Food Interaction and all others data.
Propethonum is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Propethonum is an antimuscarinic, anticholinergic drug. Propethonum is no longer available in the US market.
Propethonum is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Propethonum is an antimuscarinic, anticholinergic drug.
| Trade Name | Propethonum |
| Generic | Tridihexethyl |
| Type | |
| Formula | C21H36NO |
| Weight | Average: 318.5166 Monoisotopic: 318.279689779 |
| Groups | Withdrawn |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus
How Propethonum works
Propethonum binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Propethonum inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.
Innovators Monograph
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