Protohemin

Protohemin Uses, Dosage, Side Effects, Food Interaction and all others data.

Protohemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

Table Of contents

• Protohemin
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Protohemin
Availability	Prescription only
Generic	Hemin
Hemin Other Names	chloro(protoporphyrinato)iron(III), Hämin, Hemina, hémine, protohemin
Related Drugs	chlorpromazine, Thorazine, Givlaari, givosiran, Panhematin
Type
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Protohemin is an iron-containing porphyrin injection used for the relief of recurrent attacks of acute intermittent porphyria (AIP) associated with the menstrual cycle when carbohydrate therapy is not effective.

Used in the management of porphyria attacks, particularly in acute intermittent porphyria.

Protohemin is also used to associated treatment for these conditions: Coproporphyria, Hereditary, Porphyrias, Acute, Variegate Porphyria

Food Interaction

No interactions found.

Protohemin Drug Interaction

Moderate: clopidogrel, clopidogrelUnknown: buspirone, buspirone, docusate, docusate, metoprolol, metoprolol, mirtazapine, mirtazapine, acetaminophen, acetaminophen, albuterol, albuterol, sertraline, sertraline

Protohemin Disease Interaction

Moderate: coagulation defects

Innovators Monograph

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