Protophylline Alcohol And Sugar Free

Protophylline Alcohol And Sugar Free Uses, Dosage, Side Effects, Food Interaction and all others data.

Protophylline Alcohol And Sugar Free is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.

Protophylline Alcohol And Sugar Free, a xanthine derivative, is a bronchodilator used for relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema. Protophylline Alcohol And Sugar Free is a xanthine derivative with pharmacologic actions similar to theophylline and other members of this class of drugs. Its primary action is that of bronchodilation, but it also exhibits peripheral vasodilatory and other smooth muscle relaxant activity to a lesser degree.

Trade Name Protophylline Alcohol And Sugar Free
Availability Discontinued
Generic Dyphylline
Dyphylline Other Names Dihydroxypropyl theopylin, Diprofilina, Diprophylline, Diprophyllinum, Dyphylline
Related Drugs Trelegy Ellipta, amoxicillin, prednisone, doxycycline, ciprofloxacin, azithromycin, ceftriaxone, levofloxacin, Symbicort, Breo Ellipta
Type
Formula C10H14N4O4
Weight Average: 254.2426
Monoisotopic: 254.101504956
Protein binding

84%

Groups Approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Protophylline Alcohol And Sugar Free
Protophylline Alcohol And Sugar Free

Uses

Protophylline Alcohol And Sugar Free is a theophylline derivative used to treat asthma, bronchospasm, and COPD.

For relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema.

Protophylline Alcohol And Sugar Free is also used to associated treatment for these conditions: Bronchial Asthma, Bronchospasm, Cheyne-Stokes Respiration

How Protophylline Alcohol And Sugar Free works

The bronchodilatory action of dyphylline, as with other xanthines, is thought to be mediated through competitive inhibition of phosphodiesterase with a resulting increase in cyclic AMP producing relaxation of bronchial smooth muscle as well as antagonism of adenosine receptors.

Toxicity

LD50=1954 mg/kg (orally in mice)

Protophylline Alcohol And Sugar Free Hypertension interaction

[Moderate] Like other methylxanthines, dyphylline at high dosages may be associated with positive inotropic and chronotropic effects on the heart.

Therapy with dyphylline and products containing dyphylline should be administered cautiously in patients with severe cardiac disease, hypertension, hyperthyroidism, or recent myocardial infarction.

The relationship between plasma dyphylline levels and therapeutic as well as toxic effects has not been determined.

Protophylline Alcohol And Sugar Free Disease Interaction

Major: renal dysfunction, PUDModerate: cardiotoxicity, GERD

Half Life

2 hours (range 1.8 - 2.1 hours)

Elimination Route

Protophylline Alcohol And Sugar Free exerts its bronchodilatory effects directly and, unlike the­ophylline, is excreted unchanged by the kidneys without being metabolized by the liver. Approximately 88% of a single oral dose can be recovered from the urine unchanged.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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