Provera IM Injection 150 mg/ml
Provera IM Injection 150 mg/ml Uses, Dosage, Side Effects, Food Interaction and all others data.
| Trade Name | Provera IM Injection 150 mg/ml |
| Generic | Medroxyprogesterone Acetate (Injection) |
| Weight | 150 mg/ml |
| Type | IM Injection |
| Therapeutic Class | Female Sex hormones |
| Manufacturer | Techno Drugs Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
Medroxyprogesterone Acetate indicated for: Ovulation suppression The treatment of endometriosis. Adjunctive and/or pallivative treatment of recurrent and/or metastatic endometrial or renal carcinoma. The treatment of hormonally-dependant recurrent breast cancer in post-menopausal women.Dosage
Provera IM Injection 150 mg/ml dosage
Ovulation suppression: Medroxyprogesterone Acetate injectables suspension should be gently shaken just before use to ensure that the dose being administered represents a uniform suspension. The recommended dose is 150 mg/ml of this injectable suspension every three months administered by intramuscular injection in the gluteal or deltoid muscle. The initial injection should be given during the first 5 days after the onset of a menstrual period; within the 5 days post partum if not breast feeding; if exclusively breast-feeding at or after six weeks post partum.Based on limited experience, some investigators favour the use of a second injection of Medroxyprogesterone Acetate before 90 days to control troublesome bleeding. The third and subsequent injections should be administered at separate 90 days intervals.If abnormal bleeding persists, appropriate investigations should be instituted to rule out the possibility of organic pathology. Uterine curettage may be required on rare occations.Side Effects
Weight gain, feeling heaviness and pain in the abdomen, feeling pain, anxiety Amenorrhea Spotting Excessive bleeding Infection in the injected site Headache, Blurring of vision Pain in the back of the leg Delay in pregnancy after withdrawing injectable contraceptive.Precaution
Unexpected vaginal bleeding during therapy, patient with a pre-existing medical condition that might be adversely affected by fluid retention, patients with a history of treatment for clinical depression diabetic patient. It may decrease the level of the following endocrine biomarkers: Plasma /urinary steroid (eg: cortisol, oestrogen, pregnanediol , progesterone & testosterone ) Plasma /urinary gonadotrophin (eg: LH & FSH) & sex hormonebinding- globulin (SHBG)Interaction
Aminoglutethimide administered concomitantly with high doses of medroxyprogestrone acetate may significant depress the serum concentration of medroxyprogestrone acetate. User should be warned of the possibility of decreases efficacy with the use of amoniglutethimide.Pregnancy & Breastfeeding use
Not recommended for the first 4 months.Contraindication
Known or suspected pregnancy, Undiagnosed vaginal bleeding, Known or suspected malignancy of breast ( when used for ovulation suppression or gynaecology indications), Severe liver dysfunction, Known hypersensitivity to medroxyprogesterone acetate or any component of the drug.Storage Condition
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.Innovators Monograph
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