Proxalutamide Uses, Dosage, Side Effects and more
Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide (GT0918) in Subjects With Metastatic Castrate Resistant Prostate Cancer).
| Attribute | Details |
|---|---|
| Trade Name | Proxalutamide |
| Generic | Proxalutamide |
| Proxalutamide Other Names | Proxalutamide |
| Type | |
| Formula | C24H19F4N5O2S |
| Weight | Average: 517.5 Monoisotopic: 517.119558698 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
How Proxalutamide works
Proxalutamide is an antagonist at the androgen receptor which leads to inhibition of androgen-induced receptor activation and results in formation of inactive complexes that are not able to translocate to the nucleus. It also induces androgen receptor downregulation, furthering adrogen-induced receptor activation. This drug is being investigated for its potential antineoplastic activity and is being investigated specifically against prostate cancer and COVID-19.
