Prurex

Uses

Prurex lotion is used for the treatment of itching and skin irritation caused by, for example sunburn, dry eczema, itchy dermatitis, allergic rashes, hives, nettle rash, chickenpox, insect bites and stings, heat rashes and personal itching. Prurex lotion is also used for the treatment of pruritus after scabies.

Prurex is also used to associated treatment for these conditions: Pruritis of the skin, Scabies

How Prurex works

Prurex is an antiparasitic that is toxic to the scabies mite. Prurex also relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching.

Dosage

Prurex dosage

Pruritus: Adults (including the elderly) and children: Apply to the affected area 2-3 times daily.Prurex lotion will provide relief from irritation for 6-10 hours after each application. Prurex lotioncan be used in children. There are no special dosage recommendations in the elderly.

Pruritus after scabies: Adults (including the elderly): After the patient has taken a warm bath, theskin should be well dried and Prurex lotion rubbed into the entire body surface (excluding theface and scalp) until no traces of the preparation remain visible on the surface. The applicationshould be repeated once daily, preferably in the evening, for a total of 3-5 days. Depending onthe response, special attention should be paid to sites that are particularly susceptibly toinfestation by the mites (eg interdigital spaces, wrists, axillae and genitalia). Areas where there ispus formation should be covered with a dressing impregnated with Prurex lotion. While thetreatment is in progress the patient may take a bath shortly before the next application. Aftercompletion of the treatment, a cleansing bath should be taken followed by a change of bed linenand underclothing.

Pruritus after scabies: Children: Application as described for adults but in children under 3 years of age Prurex lotionshould not be applied more than once a day

Side Effects

Occasionally irritation of the skin or contact allergy may occur. In such cases the preparation should be discontinued.

Precaution

For external use only. Pregnancy.

Food Interaction

Elimination Route

10 % absorbed when applied locally.

Pregnancy & Breastfeeding use

Pregnancy Category C. There is no experience to judge the safety of Prurex lotion in pregnancy, therefore Prurex lotion is not recommended during pregnancy, especially in the first three months. It is not known whether the active substance passes into breast milk. Nursing mothers should avoid applying Prurex lotion in the area of the nipples.

Contraindication

Acute exudative dermatoses. Prurex 10% lotion is contra-indicated in patients with known hypersensitivity to crotamiton. Prurex 10% lotion should not be used in or around the eyes since contact with the eyelids may give rise to conjunctival inflammation.

Special Warning

Children: Application as described for adults but in children under 3 years of age Cronix lotion should not be applied more than once a day.

Acute Overdose

No information is available on overdosage following topical application. Oral ingestion of the drug may cause burning sensation of the mouth, irritation of the buccal, esophageal, and gastric mucosa, nausea, vomiting and abdominal pain. No known specific antidote. Empty stomach by emesis or gastric lavage followed by symptomatic treatment.

Storage Condition

Store at 15-30° C.

Innovators Monograph

You find simplified version here Prurex