PVP K30
PVP K30 Uses, Dosage, Side Effects, Food Interaction and all others data.
A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander. See povidone for full details.
Povidone itself has no microbicidal activity. Povidone-iodine exhibits rapid, potent, broad-spectrum antimicrobial properties . The clinical effectiveness of povidon-iodine on wound healing remains somewhat controversial; in few clinical studies investigating the effects of povidone-iodine on wound healing, topical administration of the complex was associated with no significant infections, but slower healing and mild to moderate discomfort on application .
Trade Name | PVP K30 |
Generic | Povidone K30 |
Povidone K30 Other Names | Plasdone K29-32, Plasdone K29/32, Polyvinylpyrrolidone K 30, Polyvinylpyrrolidone K30, Povidone K29-32, Povidone K29/32, PVP K-30, PVP K30, PVP-K 30 |
Type | |
Protein binding | This pharmacokinetic data does not apply to povidone. |
Groups | Approved, Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
When in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.
How PVP K30 works
Povidone-iodine is a water-soluble complex that mediates a bactericidal or virucidal action following the gradual liberation of free iodine from the complex at the application site to react with the pathogen . Please refer to the drug entry for Povidone-iodine for the full mechanism of action of the complex.
Toxicity
Oral LD50 in mouse, rat, and rabbit are >40 mg/kg, 100 mg/kg, and 1040 mg/kg, respectively . No cases of overdose in humans have been reported.
Food Interaction
No interactions found.Volume of Distribution
This pharmacokinetic data does not apply to povidone.
Elimination Route
This pharmacokinetic data does not apply to povidone.
Half Life
This pharmacokinetic data does not apply to povidone.
Clearance
This pharmacokinetic data does not apply to povidone.
Elimination Route
This pharmacokinetic data does not apply to povidone.
Innovators Monograph
You find simplified version here PVP K30