Quinoderm
Quinoderm Uses, Dosage, Side Effects, Food Interaction and all others data.
Quinoderm is a topical depigmentating agent that produces a reversible depigmentation of the skin by inhibiting enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine and suppressing melanocyte metabolic processes.
| Trade Name | Quinoderm |
| Generic | Hydroquinone |
| Hydroquinone Other Names | 1,4-benzenediol, Hydroquinone, Quinol |
| Weight | 10%w/w, 0.5%w/w, , 0.05% |
| Type | Cream |
| Formula | C6H6O2 |
| Weight | Average: 110.1106 Monoisotopic: 110.036779436 |
| Groups | Approved, Investigational |
| Therapeutic Class | Hydroquinone Preparations |
| Manufacturer | Pharmasynth Formulations, Martin Dow Pharmaceuticals (pak) Ltd,, Alliance Pharmaceuticals |
| Available Country | India, Pakistan, United Kingdom |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Quinoderm is used -
- For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other unwanted areas of melanin hyperpigmentation.
- To reduce hyperpigmentation caused by photosensitization associated with inflammation or with the use of certain cosmetics.
Quinoderm is also used to associated treatment for these conditions: Acne Vulgaris, Melasma, Skin hyperpigmentation, Moderate Melasma, Severe Melasma
How Quinoderm works
Quinoderm reduces melanin pigment production through inhibition of the tyrosinase enzyme, which is involved in the initial step of the melanin pigment biosynthesis pathway. Quinoderm takes several months to take effect.
Dosage
Quinoderm dosage
Apply a thin film of Quinoderm Cream to the effected area once daily, at least 30 minutes before bedtime. Gently wash the face and neck with a mild cleanser. Rinse and pat the skin dry. Apply Quinoderm Cream to the hyperpigmented areas of melasma including about ½ inch of normal appearing skin surrounding eachlesion. Rub lightly and uniformly into the skin.
Therapy should be discontinued when control is achieved. During the day, use asunscreenof SPF 30, and wear protective clothing. Avoid sunlight exposure. Patients may use moisturizers and/or cosmetics during the day. Quinoderm Cream is for topical use only. It is not for oral,ophthalmic, or intravaginal use.
Side Effects
No systemic adverse reactions have been reported. Occasional hypersensitivity (localized contact dermatitis) may occur in which case the medication should be discontinued.
Precaution
Quinoderm is a skin bleaching agent which may produce unwanted cosmetic effects if not used as directed. The physician should be familiar with the contents of this insert before prescribing or dispensing this medication.
Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin to check in 24 hours. Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised. If no bleaching or lightening effect is noted after 2 months of treatment, the medication should be discontinued.
Contact with the eyes and lips should be avoided. Quinoderm should not be applied to cut or abraded skin.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Lactation: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.
Contraindication
Quinoderm is contraindicated to patients with prior history of hypersensitivity or allergic reaction to hydroquinone or other ingredients in the preparation.
Acute Overdose
There have been no systemic reactions from the use of topical hydroquinone. Some patients may experience a transient reddening of skin and mild burning sensation which does not preclude treatment.
Storage Condition
Store between 20-25° C. Protect from light.
Innovators Monograph
You find simplified version here Quinoderm
Quinoderm contains Hydroquinone see full prescribing information from innovator Quinoderm Monograph, Quinoderm MSDS, Quinoderm FDA label
FAQ
What is Quinoderm used for?
Quinoderm is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin. Quinoderm also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C₆H₄(OH)₂. It has two hydroxyl groups bonded to a benzene ring in a para position.
How safe is Quinoderm?
Quinoderm is deemed safe in the United States. There isn't any clinical evidence currently to suggest that Quinoderm is harmful to humans. However, minor side effects are still possible. It may cause a temporary uptick in redness or dryness at first, especially if you have sensitive skin.
How does Quinoderm work?
Quinoderm bleaches your skin by decreasing the number of melanocytes present.
What are the common side effects of Quinoderm?
Common side effects of Quinoderm include:
- Mild skin irritation and sensitization (burning, stinging)
- Dermatitis.
- Dryness.
- Redness.
- Inflammatory reaction.
Is Quinoderm safe during pregnancy?
Whitening and brightening solutions with Quinoderm are safe to use during pregnancy and won't harm the foetus.
Is Quinoderm safe during breastfeeding?
Quinoderm is not contraindicated during breastfeeding and if Quinoderm is required by the mother, it is not a reason to discontinue breastfeeding. However, some experts feel that long-term use of Quinoderm is difficult to justify in a nursing mother.
Can Quinoderm make me blind?
Inhaling Quinoderm can irritate the nose and throat.
Is Quinoderm hazardous?
Quinoderm is also a skin irritant in humans. Chronic (long-term) occupational exposure to Quinoderm dust can result in eye irritation, corneal effects, and impaired vision.
Can I leave Quinoderm on overnight?
Apply Quinoderm cream once daily to clean, dry skin, preferably at bedtime, and leave on overnight.
Can I use Quinoderm everyday?
Quinoderm a tyrosinase inhibitor, in a 4% cream can be used safely twice daily for up to 6 months to treat post-inflammatory hyperpigmentation. The efficacy of this treatment can be enhanced by using a retinoid nightly and a mid-potent steroid, which is applied twice daily for 2 weeks, then at weekends only.
How fast does Quinoderm work?
It takes about four weeks on average for the ingredient to take effect.
How long should I use Quinoderm?
You can use the product for up to four months, and then begin to taper off use.
Can Quinoderm be used in the morning?
Apply Quinoderm in the evening after Retin-A and in the morning for 2 to 6 weeks prior to the procedure.
How often can I use Quinoderm?
Quinoderm a tyrosinase inhibitor, in a 4% cream can be used safely twice daily for up to 6 months to treat post-inflammatory hyperpigmentation.
How long does Quinoderm take to work?
Quinoderm takes about four weeks on average for the ingredient to take effect.
Can I take Quinoderm for long time?
You shouldn't use products with this ingredient for more than five months at a time.
When should I stop taking Quinoderm?
Quinoderm stop application after five months. If your skin lightens, stop using Quinoderm regularly and only use it if the dark spots reappear. Wait two or three months to use it in the same areas.
Who should not take Quinoderm?
Do not use Quinoderm topical on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. Call your doctor if your symptoms do not improve after 2 months, or if your condition gets worse.
What happens if I miss a dose?
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.
What happens if I overdose of Quinoderm?
An overdose of Quinoderm topical is not expected to be dangerous. Seek emergency medical attention if anyone has accidentally swallowed the medication.
What happen If I stop taking Quinoderm?
Prolonged regular use of Quinoderm may lead to exogenous ochronosis, which can cause blue-black pigmentation and papules, red bumps on the skin.
Is Quinoderm hard on my heart?
Quinoderm can cause dangerous effects on your heart, especially if you also use certain other medicines. Seek emergency medical attention if you have fast or pounding heartbeats and sudden dizziness
Can Quinoderm affect my kidneys?
Quinoderm produce significant histological alterations that might affect the liver and kidney.
Can Quinoderm affects my liver?
Quinoderm can remove the top layer of skin, increasing the risk of skin cancer and cause fatal liver and kidney damage.
