Raidon
Raidon Uses, Dosage, Side Effects, Food Interaction and all others data.
Raidon is dopamine receptor (D2) antagonist which selectively inhibits dopamine at the D2 receptor. It acts principally at receptors in the chemoreceptor trigger zone (CTZ) and also at receptors in the stomach.
Raidon is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
| Trade Name | Raidon |
| Generic | Domperidone |
| Domperidone Other Names | Domperidona, Domperidone, Domperidonum |
| Type | Dsr Capsule |
| Formula | C22H24ClN5O2 |
| Weight | Average: 425.911 Monoisotopic: 425.161852744 |
| Protein binding | 91%-93% |
| Groups | Approved, Investigational, Vet approved |
| Therapeutic Class | Motility Stimulants, Motility stimulants/Dopamine antagonist, Prokinetic drugs |
| Manufacturer | Asclepius Remedies Pvt Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Stimulation of gut motility in-
- Non-ulcer dyspepsia
- Oesophageal reflux, reflux oesophagitis and gastritis
- Diabetic gastroparesis
- Functional dyspepsia
- Speeding barium transit in follow through radiological studies
Prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radiotherapy and antiparkinsonism therapy.
In the prophylactic treatment of migraine.
Raidon is also used to associated treatment for these conditions: Diabetic Gastroparesis, Dyspepsia, Erosive Esophagitis, Gastrointestinal Symptoms, Non-erosive Reflux Esophagitis Disease (NERD), Upper gastrointestinal motility disorders
How Raidon works
Raidon acts as a gastrointestinal emptying (delayed) adjunct and peristaltic stimulant. The gastroprokinetic properties of domperidone are related to its peripheral dopamine receptor blocking properties. Raidon facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting
Dosage
Raidon dosage
Adults: 10 - 20 mg every 4 - 8 hours daily
Children: 0.2 - 0.4 mg/kg every 4 - 8 hours daily.
Raidon tablet and suspension should be taken 15 - 30 minutes before a meal. For acute nausea and vomiting, maximum period of treatment is 12 weeks.
Side Effects
Raidon may produce hyperprolactinemia which may cause galactorrhea & breast enlargement, soreness and reduced libido. It may rarely cause dry mouth, thirst, headache, nervousness, drowsiness, diarrhea, skin rash and itching.
Toxicity
Side effects include galactorrhea, gynecomastia, or menstrual irregularities.
Precaution
Raidon should be used with absolute caution in case of children because there may be an increased risk of extra-pyramidal reactions in young children because of an incompletely developed blood brain barrier.
Interaction
Raidon may reduce the hypoprolactinaemic effect of bromocriptine. Anti-muscarinics and opioid analgesics may antagonize the action of Raidon on gastrointestinal function.
Food Interaction
- Take before a meal. Take 15-30 minutes before meals.
Half Life
7 hours
Pregnancy & Breastfeeding use
Use in pregnancy: The safety of this drug has not been established for pregnant women. So it is not recommended during pregnancy.
Use in lactation: Raidon may precipitate galactorrhea and improve postnatal lactation, which is secreted in breast milk but in very small quantities insufficient to be considered harmful.
Contraindication
Raidon is contraindicated to the patients who have hypersensitivity to this drug and in case of neonates.
Acute Overdose
Overdose has been reported primarily in infants and children. Symptoms of overdosage may include disorientation, somnolence and extrapyramidal reactions. There is no specific antidote to domperidone, but in the event of overdose, the administration of activated charcoal may be useful. Anticholinergics, antiparkinson drugs may be useful in controlling extrapyramidal reactions. The patient should be observed closely and supportive measures employed.
Storage Condition
Store in a cool dry place protected from light. Keep out of reach of children.
Innovators Monograph
You find simplified version here Raidon
Raidon contains Domperidone see full prescribing information from innovator Raidon Monograph, Raidon MSDS, Raidon FDA label
FAQ
What is Raidon used for?
Raidon help to stop feeling or being sick like as nausea or vomiting.It can also be used to treat stomach pain if you're having end of life care. Raidon is sometimes used to increase milk supply.
Is Raidon safe to take?
For most people, taking Raidon is safe.If you have heart problems or are taking other medicines, you should first check with your healthcare professional that this medicine is appropriate.
What are the side effects of Raidon?
Common side effects of Raidon are include:
- swelling of the ankles/feet.
- unusual tiredness.
- mental/mood changes (e.g., nervousness, irritability)
- hot flashes.
- breast swelling/pain.
- unusual leakage of milk from the breast.
- changes in menstrual periods.
- decreased sexual ability.
Is Raidonsafe during pregnancy?
Raidon is not usually recommended in pregnancy.
Why Raidon is not safe in pregnancy?
Raidon is contraindicated for use in pregnant women and in women suspected of being pregnant, due to teratogenicity observed in reproductive toxicity studies.
Is Raidon safe during breastfeeding?
A very small amount of the Raidon you take can pass into your breast milk, but there is no record of harmful side effects in the baby from the mother taking Raidon.
Can I drink alcohol with Raidon?
It is best to avoid alcohol when taking Raidon. Drinking alcohol can make side effects worse, such as sleepiness or an irregular heartbeat.
How long does Raidon take to work?
Raidon often takes at least three or four days before you notice any effect. It usually takes about two weeks to get a maximum effect, but some find it takes even longer.
Can I take Raidon before bed?
Raidon is best taken 15 to 30 minutes before meals and id necessary at bedtime.
Is Raidon good for acid reflux?
It decreases postprandial reflux time and is therefore used to treat regurgitation and vomiting.
Can I take Raidon after eating?
Raidon is best taken about 15 to 30 minutes before meals, with a glass of water. If you take Raidon after a meal, it will still work, but it may take longer to have an effect.
Is Raidon good for gastritis?
Raidon has a good advantage in the treatment of reflux gastritis and is more effective than conventional treatment.Raidon is a kind of drug to strengthen gastric motility.
What does Raidon do to your body?
Raidon is a medicine that increases the movements or contractions of the stomach and bowel. Raidon is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease.
Is Raidon safe for kidneys?
Raidon are not significantly renally cleared and can be used in CKD.
Does Raidon help anxiety?
Raidon is used to treat severe anxiety like as emotional state where you may sweat, tremble, feel anxious and have a fast heartbeat or agitation.
Does Raidon raise blood pressure?
Raidon increases blood pressure and heart rate without inducing nocturnal hypertension in apomorphine treated patients with idiopathic Parkinson's disease.
Is Raidon a narcotic?
Raidon is not a controlled substance e.g. sleeping pills, valium, narcotics.
Does Raidon cause depression?
Raidon can cause central nervous system side effects such as fatigue, irritability, or depression.
Can I take Raidon for a long time?
You should usually take Raidon for up to a week.Because Raidon can cause an irregular heartbeat if you take it for longer or at a high dose.
What happens when I stop taking Raidon?
Most women do not experience discomfort when stopping the medication, gradual weaning from the medication will help the mother's milk supply to adjust without frustrating the baby or causing her discomfort. It is very important to stop the Raidon slowly.
