Ranicon
Ranicon Uses, Dosage, Side Effects, Food Interaction and all others data.
Ranicon binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Oxphencyclimine inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.
Ranicon is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Ranicon is an antimuscarinic, anticholinergic drug.
| Trade Name | Ranicon |
| Generic | Oxyphencyclimine |
| Oxyphencyclimine Other Names | Oxifencicliminum, Oxyphencyclimine, Oxyphencycliminum |
| Weight | 5mg |
| Type | Tablet |
| Formula | C20H28N2O3 |
| Weight | Average: 344.4479 Monoisotopic: 344.209992772 |
| Groups | Approved |
| Therapeutic Class | Anticholinergics (antimuscarinics)/ Anti-spasmodics |
| Manufacturer | Renata Limited |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Ranicon is used for the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders.
Ranicon is also used to associated treatment for these conditions: Smooth muscle spasticity
How Ranicon works
Ranicon binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Oxphencyclimine inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.
Dosage
Ranicon dosage
Adult: 10 mg twice daily orally.
Side Effects
Xerostomia, decreased sweating, urinary hesitancy and retention, blurred vision, cycloplegia, increased ocular tension, loss of taste, headache, nervousness, mental confusion, impotence, suppression of lactation, urticaria, constipation.
Precaution
Elderly; autonomic neuropathy; hepatic or renal disease; hyperthyroidism, CHF, thyrotoxicosis, MI, tachyarrhythmias, hypertension, prostatic hypertrophy; hiatal hernia. May impair ability to drive or operate machinery. Pregnancy and lactation. Down's syndrome.
Interaction
Enhanced effect with concurrent admin of other drugs with antimuscarinic properties and MAOIs. May affect absorption of other drugs. Antagonistic effect with parasympathomimetics.
Pregnancy & Breastfeeding use
Pregnancy category- Not classified
Contraindication
Closed-angle glaucoma; obstructive uropathy; GI obstruction, paralytic ileus, intestinal atony, ulcerative colitis; toxic megacolon; myasthenia gravis.
Acute Overdose
Symptoms range from increased side effects to CNS disturbances, circulatory changes, respiratory failure, paralysis and coma. treat with immediate gastric lavage and injection of physostimine 0.5-2 mg up to a total of 5 mg. Treat symptomatically and supportively.
Innovators Monograph
You find simplified version here Ranicon
