Ranicon

Ranicon Uses, Dosage, Side Effects, Food Interaction and all others data.

Ranicon binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Oxphencyclimine inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.

Ranicon is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Ranicon is an antimuscarinic, anticholinergic drug.

Ranicon
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Ranicon
Generic	Oxyphencyclimine
Oxyphencyclimine Other Names	Oxifencicliminum, Oxyphencyclimine, Oxyphencycliminum
Weight	5mg
Type	Tablet
Formula	C₂₀H₂₈N₂O₃
Weight	Average: 344.4479 Monoisotopic: 344.209992772
Groups	Approved
Therapeutic Class	Anticholinergics (antimuscarinics)/ Anti-spasmodics
Manufacturer	Renata Limited
Available Country	Bangladesh
Last Updated:	September 19, 2023 at 7:00 am

Uses

Ranicon is used for the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders.

Ranicon is also used to associated treatment for these conditions: Smooth muscle spasticity

How Ranicon works

Dosage

Ranicon dosage

Adult: 10 mg twice daily orally.

Side Effects

Xerostomia, decreased sweating, urinary hesitancy and retention, blurred vision, cycloplegia, increased ocular tension, loss of taste, headache, nervousness, mental confusion, impotence, suppression of lactation, urticaria, constipation.

Precaution

Elderly; autonomic neuropathy; hepatic or renal disease; hyperthyroidism, CHF, thyrotoxicosis, MI, tachyarrhythmias, hypertension, prostatic hypertrophy; hiatal hernia. May impair ability to drive or operate machinery. Pregnancy and lactation. Down's syndrome.

Interaction

Enhanced effect with concurrent admin of other drugs with antimuscarinic properties and MAOIs. May affect absorption of other drugs. Antagonistic effect with parasympathomimetics.

Pregnancy & Breastfeeding use

Pregnancy category- Not classified

Contraindication

Closed-angle glaucoma; obstructive uropathy; GI obstruction, paralytic ileus, intestinal atony, ulcerative colitis; toxic megacolon; myasthenia gravis.

Acute Overdose

Symptoms range from increased side effects to CNS disturbances, circulatory changes, respiratory failure, paralysis and coma. treat with immediate gastric lavage and injection of physostimine 0.5-2 mg up to a total of 5 mg. Treat symptomatically and supportively.