Recombinant Nematode Anticoagulant Protein-2
Recombinant Nematode Anticoagulant Protein-2 Uses, Dosage, Side Effects, Food Interaction and all others data.
Recombinant nematode anticoagulant protein c2 (Recombinant Nematode Anticoagulant Protein-2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity.
Trade Name | Recombinant Nematode Anticoagulant Protein-2 |
Generic | rNAPc2 |
rNAPc2 Other Names | Recombinant nematode anticoagulant protein c2, Recombinant nematode anticoagulant protein-2 |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in thrombosis (deep vein), angina, coronary artery disease, and colorectal cancer.
How Recombinant Nematode Anticoagulant Protein-2 works
Recombinant Nematode Anticoagulant Protein c2 (Recombinant Nematode Anticoagulant Protein-2) is a potent (K(i) =10 pM), inhibitor of the factor VIIa/tissue factor (fVIIa/TF) complex that requires the prerequisite binding to zymogen or activated factor X (fX). This has been shown to attenuate the activation of coagulation and to prevent death in a primate model of sepsis caused by gram-negative bacteria.
Half Life
Over 50 hours
Innovators Monograph
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