Rombellin
Rombellin Uses, Dosage, Side Effects, Food Interaction and all others data.
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Rombellin is a water-soluble B-complex vitamin which is composed of an ureido ring fused with a tetrahydrothiophene ring, which attaches a valeric acid substituent at one of its carbon atoms. Rombellin is used in cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Kreb cycle, which is the process in which energy is released from food. Rombellin not only assists in various metabolic chemical conversions, but also helps with the transfer of carbon dioxide. Rombellin is also helpful in maintaining a steady blood sugar level. Rombellin is often recommended for strengthening hair and nails. Consequenty, it is found in many cosmetic and health products for the hair and skin. Rombellin deficiency is a rare nutritional disorder caused by a deficiency of biotin. Initial symptoms of biotin deficiency include: Dry skin, Seborrheic dermatitis, Fungal infections, rashes including erythematous periorofacial macular rash, fine and brittle hair, and hair loss or total alopecia. If left untreated, neurological symptoms can develop, including mild depression, which may progress to profound lassitude and, eventually, to somnolence; changes in mental status, generalized muscular pains (myalgias), hyperesthesias and paresthesias. The treatment for biotin deficiency is to simply start taking some biotin supplements. A lack of biotin in infants will lead to a condition called seborrheic dermatitis or "cradle cap". Rombellin deficiencies are extremely rare in adults but if it does occur, it will lead to anemia, depression, hair loss, high blood sugar levels, muscle pain, nausea, loss of appetite and inflamed mucous membranes.
| Trade Name | Rombellin |
| Availability | Rx and/or OTC |
| Generic | Biotin |
| Biotin Other Names | Biotin, Biotina, Biotine, Biotinum, Coenzyme R, D-Biotin, Vitamin B7, Vitamin H |
| Related Drugs | acetylcysteine, Vitamin C, ascorbic acid, multivitamin, Zinc, Fish Oil |
| Type | |
| Formula | C10H16N2O3S |
| Weight | Average: 244.311 Monoisotopic: 244.088163078 |
| Groups | Approved, Investigational, Nutraceutical |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Switzerland |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Rombellin is a B-complex vitamin found in many multivitamin products.
For nutritional supplementation, also for treating dietary shortage or imbalance.
Rombellin is also used to associated treatment for these conditions: Vitamin Deficiency, Nutritional supplementation
How Rombellin works
Rombellin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, including gluconeogenesis, lipogenesis, fatty acid biosynthesis, propionate metabolism, and catabolism of branched-chain amino acids.
Toxicity
Prolonged skin contact may cause irritation.
Food Interaction
- Avoid dietary avidin (a glycoprotein in uncooked egg-whites). Avidin binds with biotin in the gastrointestinal tract preventing biotin absorption. Avidin is denatured by cooking; therefore, cooked egg whites do not reduce biotin absorption.
Elimination Route
Systemic - approximately 50%
Innovators Monograph
You find simplified version here Rombellin
FAQ
What is Rombellin used for?
Rombellin is used for preventing and treating biotin deficiency associated with pregnancy, long-term tube feeding, malnutrition, and rapid weight loss. It is also used orally for hair loss, brittle nails, skin rash in infants (seborrheic dermatitis), diabetes, and mild depression.
How safe is Rombellin?
Rombellin is likely safe for most people when taken in doses up to 300 mg daily for up to 6 months. But it is more commonly used in lower doses of 2.5 mg daily. When applied to the skin: Rombellin is likely safe for most people when applied in cosmetic products that contain up to 0.6% biotin.
How does Rombellin work?
Stimulates keratin production in hair and can increase the rate of follicle growth. It is not stored for long in the body - most of yours is from the foods you eat. In order to be effective, it needs to be consumed.
What are the common side effects of Rombellin?
Common side effects can include skin rashes, digestive upset, problems with insulin release, and kidney problems.
Is Rombellin safe during pregnancy?
Can be dangerous to the baby, so additional supplementation of biotin isn't recommended.
Is Rombellin safe during breastfeeding?
Yes, theoretically you can take Rombellin while breastfeeding, but it may not be a good or helpful addition to your diet.
Can I drink alcohol with Rombellin?
Probably not. You should be getting the safe from your doctor before taking any supplement, and biotin deficiency is rare.
When is the best time to take Rombellin ?
Taking it is independent of the time of day. However, Rombellin in the form of food supplements should always be taken on an empty stomach or 30 minutes after a meal.
How do I take Rombellin?
Taking Rombellin by mouth or by a shot can treat and prevent low blood levels of Rombellin. Up to 10 mg of Rombellin by mouth daily has been used to treat and prevent deficiency. A Rombellin shot can only be given by a healthcare provider.
How often can I take Rombellin?
Still, people who support its use often recommend taking 2 to 5 milligrams (mg) of biotin in supplement form daily in order to strengthen hair and achieve results.
How long does Rombellin take to work?
Although research is limited, studies from 2012 and 2015 suggest that results may be seen in as little as 90 days. This includes an increase in growth and shine. It's thought that the longer you consume a higher dose, the better your results will be.
Is it better to take Rombellin in the morning or at night?
Since Biotin is a water-soluble member of the B-Vitamin family it is best to take Biotin with your first meal of the day.
How long does Rombellin take to leave my system?
Rombellin doesn't stay in a person's body forever: It leaves the body after some time. It's uncertain exactly how long people need to wait for the vitamin to clear their blood. Some lab test manufacturers argue that 8 hours is enough.
Who should not take Rombellin?
You should not use this product if you are allergic to biotin. Before using biotin, talk to your .healthcare provider. Your dose needs may be different: if you have kidney disease; if you have had stomach surgery; or if you smoke.
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra biotin to make up the missed dose.
What happens if I overdose?
Since biotin is a water-soluble vitamin, an overdose is unlikely to occur.
Do I have to take Rombellin forever?
It is often recommended to consult your doctor before starting Rombellin supplements so that you do not overdoes it. And once started, you might consider taking the supplements till you see the desired difference in your mane.
Does Rombellin grow hair?
Rombellin may assist in regrowth.
Is Rombellin safe for kidneys?
Patients who take biotin in an moderate amount but have kidney failure who having a delayed clearance of the vitamin. Biotin, vitamin B7 or vitamin H is a water-soluble vitamin eliminated through the kidney with a half-life between 8 and 24 hours, variable from person to person and increased with kidney failure.
Will Rombellin make me gain weight?
No, there is no evidence to suggest taking Rombellin supplements can lead to weight gain. In fact, Rombellin is sometimes touted as a weight-loss supplement. However, there is no research to confirm biotin has any effect on weight.
Is too much bad for my hair?
In terms of your hair and scalp, taking too much Rombellin won't result in drastic damage.
Does Rombellin cause facial hair growth?
Rombellin can most definitely increase the rate at which your beard grows while making each hair thicker and healthier.
Does Rombellin affect sleep?
Research shows that a deficiency in B-complex vitamins, including biotin, can cause sleep and anxiety problems.
Can Rombellin cause acne?
There is minimal evidence that supports the claim that taking biotin supplements will worsen acne.
Is Rombellin bad for my liver?
Despite the fact that Rombellin supplementation had no effect on liver toxicity markers, histological analysis showed noticeable differences between groups.
