Secobarbital Sodium-Yimin Pharm

Secobarbital Sodium-Yimin Pharm Uses, Dosage, Side Effects, Food Interaction and all others data.

Secobarbital Sodium-Yimin Pharm (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.

Secobarbital Sodium-Yimin Pharm, a barbiturate, is used for the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.

Trade Name Secobarbital Sodium-Yimin Pharm
Availability Discontinued
Generic Secobarbital
Secobarbital Other Names Quinalbarbitone, Secobarbital, Secobarbitalum, Secobarbitone
Related Drugs trazodone, hydroxyzine, amitriptyline, lorazepam, diazepam, melatonin, zolpidem, promethazine, diphenhydramine, fentanyl
Type
Formula C12H18N2O3
Weight Average: 238.2829
Monoisotopic: 238.131742452
Groups Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country China
Last Updated: September 19, 2023 at 7:00 am
Secobarbital Sodium-Yimin Pharm
Secobarbital Sodium-Yimin Pharm

Uses

Secobarbital Sodium-Yimin Pharm is a barbiturate used for the short-term treatment of insomnia.

For the Short-term treatment of intractable insomnia for patients habituated to barbiturates

Secobarbital Sodium-Yimin Pharm is also used to associated treatment for these conditions: Insomnia, Preanesthetic medication therapy

How Secobarbital Sodium-Yimin Pharm works

Secobarbital Sodium-Yimin Pharm binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.

Toxicity

Symptoms of an overdose typically include sluggishness, incoordination, difficulty in thinking, slowness of speech, faulty judgment, drowsiness or coma, shallow breathing, staggering, and in severe cases coma and death.

Food Interaction

  • Avoid alcohol. Taking with alcohol may cause additive CNS depression.
  • Take on an empty stomach. This may increase the rate of absorption.

Secobarbital Sodium-Yimin Pharm Alcohol interaction

[Major] GENERALLY AVOID:

Concurrent acute use of barbiturates and ethanol may result in additive CNS effects,

including impaired coordination, sedation, and death.

Tolerance of these agents may occur with chronic use.

The mechanism is related to inhibition of microsomal enzymes acutely and induction of hepatic microsomal enzymes chronically.



The combination of ethanol and barbiturates should be avoided.

Secobarbital Sodium-Yimin Pharm Hypertension interaction

[Major] The intravenous administration of barbiturates may produce severe cardiovascular reactions such as bradycardia, hypertension, or vasodilation with fall in blood pressure, particularly during rapid infusion.

Parenteral therapy with barbiturates should be administered cautiously in patients with hypertension, hypotension, or cardiac disease.

The intravenous administration of barbiturates should be reserved for emergency treatment of acute seizures or for anesthesia.

Elimination Route

Barbiturates are metabolized primarily by the hepatic microsomal enzyme system, and the metabolic products are excreted in the urine and, less commonly, in the feces.

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*** Taking medicines without doctor's advice can cause long-term problems.
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