Selenic acid Uses, Dosage, Side Effects and more
Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of Selenium, an essential trace mineral for human health.
Selenium is an essential trace mineral that plays a critical role in antioxidant actions, anti-inflammatory effects, immune function, and the production of active thyroid hormone .
| Trade Name | Selenic acid |
| Generic | Selenic acid |
| Type | |
| Formula | H2O4Se |
| Weight | Average: 144.97 Monoisotopic: 145.91183038 |
| Protein binding | No pharmacokinetic data available. |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Selenic acid is an ingredient found in a variety of supplements and vitamins.
Indicated for use as a nutritional supplement.
Selenic acid is also used to associated treatment for these conditions: Mineral supplementation, Nutritional supplementation, Vitamin supplementation
How Selenic acid works
Selenium is a constituent of selenoproteins thus has structural and enzymatic roles. It acts as an antioxidant via the actions of selenoproteins for protection against oxidative stress, and acts as a catayst for the production of active thyroid hormone []. It may also play a role in sperm motility .
Toxicity
Injectable selenium is more acutely toxic than oral administration, with an intramuscular LD50 of 0.5 mg/kg BW in lambs .
Food Interaction
No interactions found.Volume of Distribution
No pharmacokinetic data available.
Elimination Route
Following single oral administration of sodium selenate concentrations ranging from 1 mg Se/kg to 4 mg Se/kg in lambs, the peak plasma concentrations ranged from 0.79 mg Se/L to 2.54 mg Se/L . The time to reach peak plasma concentrations ranged from 7 to 12 hours .
Half Life
Following single oral administration of 1 mg Se/kg of sodium selenate in lambs, the elimination half life was 313 hours. The elimination half life was 142 hours following a single oral dosing of 4 mg Se/kg as sodium selenate .
Clearance
No pharmacokinetic data available.
