Selenic acid
Selenic acid Uses, Dosage, Side Effects, Food Interaction and all others data.
Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of Selenium, an essential trace mineral for human health.
Selenium is an essential trace mineral that plays a critical role in antioxidant actions, anti-inflammatory effects, immune function, and the production of active thyroid hormone .
Trade Name | Selenic acid |
Generic | Selenic acid |
Type | |
Formula | H2O4Se |
Weight | Average: 144.97 Monoisotopic: 145.91183038 |
Protein binding | No pharmacokinetic data available. |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Selenic acid is an ingredient found in a variety of supplements and vitamins.
Indicated for use as a nutritional supplement.
Selenic acid is also used to associated treatment for these conditions: Mineral supplementation, Nutritional supplementation, Vitamin supplementation
How Selenic acid works
Selenium is a constituent of selenoproteins thus has structural and enzymatic roles. It acts as an antioxidant via the actions of selenoproteins for protection against oxidative stress, and acts as a catayst for the production of active thyroid hormone []. It may also play a role in sperm motility .
Toxicity
Injectable selenium is more acutely toxic than oral administration, with an intramuscular LD50 of 0.5 mg/kg BW in lambs .
Food Interaction
No interactions found.Volume of Distribution
No pharmacokinetic data available.
Elimination Route
Following single oral administration of sodium selenate concentrations ranging from 1 mg Se/kg to 4 mg Se/kg in lambs, the peak plasma concentrations ranged from 0.79 mg Se/L to 2.54 mg Se/L . The time to reach peak plasma concentrations ranged from 7 to 12 hours .
Half Life
Following single oral administration of 1 mg Se/kg of sodium selenate in lambs, the elimination half life was 313 hours. The elimination half life was 142 hours following a single oral dosing of 4 mg Se/kg as sodium selenate .
Clearance
No pharmacokinetic data available.
Innovators Monograph
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