Selisistat Uses, Dosage, Side Effects and more

Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents.

Trade Name Selisistat
Generic Selisistat
Selisistat Other Names Selisistat
Type
Formula C13H13ClN2O
Weight Average: 248.71
Monoisotopic: 248.0716407
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am

Innovators Monograph

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