Setiptiline
Setiptiline Uses, Dosage, Side Effects, Food Interaction and all others data.
Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.
Setiptiline is a tertacyclic antidepressant . It acts to reduce the symptoms of major depressive disorder.
Trade Name | Setiptiline |
Generic | Setiptiline |
Setiptiline Other Names | Setiptilina, Setiptiline, Setiptilinum |
Type | |
Formula | C19H19N |
Weight | Average: 261.368 Monoisotopic: 261.151749616 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of depression .
How Setiptiline works
Setiptiline is an antagonist at the α2 adrenergic receptor and at serotonin receptors . The antagonism of the α2 receptors likely relieves presynaptic inhibition of adrenergic neurotransmission, allowing for greater and longer sustained release of noradrenaline into the synapse. The antagonism of serotonin receptors may produce an upregulation of the receptors leading to an eventual increase in serotonergic signalling. The actual physiological mechanisms behind the antidepressant effect of setiptiline is unknown but the listed possibilities exist as likely explanations.
Innovators Monograph
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