Silybin
Silybin Uses, Dosage, Side Effects, Food Interaction and all others data.
Silybin possess hepatoprotective and antioxidant activity. The hepatoprotective effect is due to stimulation of synthesis of structural and functional proteins and phospholipids, as well as acceleration of the regeneration of hepatocytes.
Antioxidant effect is determined by interaction of bioflavones with free radicals in the liver and its detoxication. In such manner the process of peroxidation of the lipids is interupted and further liver destruction is prevented.
Clinically, these effects are manifested by improvement of the signs and symptoms and normalization of the liver variables (serum level of transaminases, gamma-globulins, and bilirubin).
| Trade Name | Silybin |
| Generic | Silymarin |
| Weight | 70mg, 140mg |
| Type | Capsule |
| Therapeutic Class | Cholagogues, Cholelitholytics & Hepatic Protectors |
| Manufacturer | Square Pharmaceuticals Ltd |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of jaundice, chronic inflammatory liver conditions, i.e. hepatitis, alcoholic liver damage and hepatic cirrhosis. It has anti-oxidant property.
Dosage
Silybin dosage
70 mg or 140 mg or 500 mg capsule should be taken 3 times daily as per the instruction of a physician. The medication should be continued until the relief of the symptoms according to the advice of a physician.
Side Effects
A mild laxative effect has occasionally been observed.
Pregnancy & Breastfeeding use
No experience is available about the use of Silybin 70 mg or 140 mg during pregnancy and lactation. Therefore, if needed Silybin 70 mg or 140 mg should be taken with caution according to the physician’s advice.
Contraindication
No adequate data of investigations are available about the use of this drug in children. Therefore, it should be used in children under 12 years of age with caution under the direct supervision of a physician.
Storage Condition
To be stored in a cool and dry place, away from direct sunlight. Keep the medicine out of reach of children.
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FAQ
What is Silybin used for?
Silybin is used for the treatment of Chronic Liver Disease and Cirrhosis of the liver.Silybin is an active concept obtained from milk thistle seed. It could protect liver cells from chemicals and drugs that are harmful.
How safe is Silybin?
Silybin is safe in humans at therapeutic doses and is well tolerated.
What are the common side effects of Silybin?
The common side effects of Silybin are include:
- Nausea.
- Diarrhea.
- Intestinal gas.
- Fullness or pain in the stomach.
- Loss of appetite.
- Rashes and itching.
Is Silybin safe during pregnancy?
Silybin has been given to pregnant women in clinical studies without any evidence of a negative reaction.
Is Silybin safe during breastfeeding?
Silybin components are not excreted into breastmilk in measurable quantities. Additionally, because Silybin components are poorly absorbed orally, milk thistle is unlikely to adversely affect the breastfed infant.
Can I drink alcohol with Silybin?
Do not consume alcohol while you are taking Silybin.While there is no specific interaction between this nutritional supplement and alcohol, the primary reason people take bra nd is to protect the liver and help it repair itself.
Does Silybin protect liver?
Silybin is an antioxidant that protects the liver from the free radical damage produced by alcohol metabolism.
How long can you take Silybin?
Adult dosage in terms of hepatoprotection is three times a day for 6-8 weeks.
What is the best time to take Silybin?
best time to take 2- 3 times daily, before meals.
Can Silybin reverse liver damage?
Silybin can help reduce liver inflammation and liver damage.
Is Silybin good for the kidneys?
Silybin may be just as important for kidney health as for liver.Silybin concentrates in kidney cells, where it aids in repairing and regeneration by increasing protein and nucleic acid synthesis.
Does Silybin cause diarrhea?
Aside from a possible allergic reaction, diarrhea, bloating, and gassiness are the most common side effects from taking Silybin.
Is silymarin good for skin?
Silybin comes with a copious amount of skin-care benefits, but its ability to regulate oil production while simultaneously providing protection against ultraviolet radiation, pollution, cellular damage, and free-radical damage is the most notable.
Does Silybin cause weight gain?
control group continued gaining weight throughout.
Who should not take Silybin?
Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
How should I take Silybin?
If you choose to use Silybin, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.
What happens if I miss a dose of Silybin?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra milk thistle to make up the missed dose.
Can I overdose on milk thistle tablets?
Using different formulations together increases the risk of an overdose. Call your doctor if the condition you are treating with Silybin does not improve, or if it gets worse while using this product.
