Siochrome

Siochrome Uses, Dosage, Side Effects, Food Interaction and all others data.

Siochrome is a haemostatic with a rapid onset of action. It contains a water soluble form of adrenochrome monosemicarbazone, a stable derivative of adrenochrome as the active substance. Adrenochrome is an oxidation product of adrenaline; it reduces normal and pathologic bleeding time by decreasing capillary permeability. It produces capillary haemostatis without exerting any of the adrenergic actions on respiration or cardiovascular system. Thus, despite its adrenaline like action on small blood vessels, does not give rise to the general systemic effects of sympathomimetic drugs.

Trade Name Siochrome
Generic Adrenochrome Monosemicarbazone
Weight vit c
Type Injection, Tablet
Therapeutic Class Anti-fibrinolytic drugs
Manufacturer Albert David Limited
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Siochrome
Siochrome

Uses

Adrenochrome is used for control capillary bleeding, haemoptysis, epistemic, haematuria, retinal hemorrhage, secondary hemorrhage from wounds

Dosage

Siochrome dosage

Oral (Adult)-

  • As a haemostatic: 10-30 mg tid.

Injection(Adult)-

  • As a haemostatic: 10 mg daily by SC/IM inj. Alternatively, 25-100 mg daily by IV Inj or drip infusion.
  • Pre-operative: 2-6 ml at suitable intervals.
  • Post-operative: 1-2 ml every 2 hrs.
  • Non-surgical: 2-4 ml tid.

Injection(Child <6 years): 1-2 ml tid.

Side Effects

Allergic reactions may occur like dyspnoea, bronchospasm, skin reaction etc.

Precaution

Because of the content of diprophylline (90 mg/ml), the dosage to premature babies, infants and young children should not exceed 0.3 ml.

Interaction

No specific drug interaction has been demonstrated.

Pregnancy & Breastfeeding use

Pregnancy Category-Not Classified. FDA has not yet classified the drug into a specified pregnancy category

Contraindication

Should not be administered to patients with hypersensitivity

Innovators Monograph

You find simplified version here Siochrome


*** Taking medicines without doctor's advice can cause long-term problems.
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