Solutricine Maux de Gorge Tétracaïne
Solutricine Maux de Gorge Tétracaïne Uses, Dosage, Side Effects, Food Interaction and all others data.
Solutricine Maux de Gorge Tétracaïne is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
| Trade Name | Solutricine Maux de Gorge Tétracaïne |
| Availability | Prescription only |
| Generic | Tetracaine |
| Tetracaine Other Names | Amethocaine, Amethocaine HCl, Diäthylaminoäthanol ester der p-butylaminobenzösäure, Dicaine, Medihaler-Tetracaine, Metraspray, Tetracaína, Tétracaïne, Tetracaine, Tetracaine HCl |
| Type | |
| Formula | C15H24N2O2 |
| Weight | Average: 264.369 Monoisotopic: 264.183778021 |
| Protein binding | Tetracaine is rapidly hydrolyzed in the plasma; therefore, protein binding could not be determined. |
| Groups | Approved, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | France |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Solutricine Maux de Gorge Tétracaïne is a local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic.
The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.
Solutricine Maux de Gorge Tétracaïne is also used to associated treatment for these conditions: Dermabrasion, Hemorrhoids, Insect Bites, Rash caused by poison ivy, Sunburn, Minor burns, Anesthetics, Local, Local Anesthesia of the Skin, Local anesthesia therapy
How Solutricine Maux de Gorge Tétracaïne works
Solutricine Maux de Gorge Tétracaïne is an ester-type anesthetic and produces local anesthesia by blocking the sodium ion channels involved in initiation and conduction of neuronal impulses.
Toxicity
The most common adverse effects with the combination cream are localized reactions such as: erythema (47%), skin discoloration (16%), and edema (14%). Systemic adverse events were less common, occurring at a rate of <1% and included vomiting, headache, dizziness, and fever. Similar to other amide and ester anesthetics, CNS excitation and/or depression may occur. It is not well known at which plasma concentration systemic toxicity occurs with tetracaine; however, the threshold is thought to be much lower than that of lidocaine which is 1000 ng/mL.
Food Interaction
No interactions found.Solutricine Maux de Gorge Tétracaïne Drug Interaction
Major: procaine penicillinModerate: lorazepam, midazolamUnknown: aspirin, charcoal, epinephrine, azithromycin, diphenhydramine, glucose, ethanol, lithium, morphine, acetaminophen, valproic acid, cyanocobalamin, riboflavin, pyridoxine, ascorbic acid, cholecalciferol, ondansetron
Volume of Distribution
Solutricine Maux de Gorge Tétracaïne is rapidly hydrolyzed in the plasma; therefore, volume of distribution could not be determined.
Elimination Route
Systemic absorption of anaesthetic from the combination cream is directly related to the duration and surface area of application. Although peak plasma concentrations for lidocaine were measured, plasma levels for tetracaine could not be determined due to low levels (<0.9 ng/mL)
Half Life
Solutricine Maux de Gorge Tétracaïne is hydrolyzed rapidly in the plasma; therefore, half-life has not been determined.
Clearance
Solutricine Maux de Gorge Tétracaïne is hydrolyzed rapidly in the plasma; therefore, clearance has not been determined.
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