SOMAVERT10mgpolvereesolventepersoluzioneiniettabile

SOMAVERT10mgpolvereesolventepersoluzioneiniettabile Uses, Dosage, Side Effects, Food Interaction and all others data.

SOMAVERT10mgpolvereesolventepersoluzioneiniettabile is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity.

Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.

Trade Name SOMAVERT10mgpolvereesolventepersoluzioneiniettabile
Availability Prescription only
Generic Pegvisomant
Pegvisomant Other Names Pegvisomant
Related Drugs octreotide, bromocriptine, Sandostatin, lanreotide, Somatuline Depot, Parlodel
Type
Formula C990H1532N262O300S7
Weight 22129.0 Da
Groups Approved
Therapeutic Class
Manufacturer
Available Country Italy
Last Updated: September 19, 2023 at 7:00 am
SOMAVERT10mgpolvereesolventepersoluzioneiniettabile
SOMAVERT10mgpolvereesolventepersoluzioneiniettabile

Uses

SOMAVERT10mgpolvereesolventepersoluzioneiniettabile is a growth hormone receptor antagonist used to treat acromegaly.

SOMAVERT10mgpolvereesolventepersoluzioneiniettabile is a growth hormone receptor antagonist used for the treatment of acromegaly.

SOMAVERT10mgpolvereesolventepersoluzioneiniettabile is also used to associated treatment for these conditions: Acromegaly

How SOMAVERT10mgpolvereesolventepersoluzioneiniettabile works

Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH. This leads to the normalization of serum IGF-1 levels.

Food Interaction

No interactions found.

SOMAVERT10mgpolvereesolventepersoluzioneiniettabile Disease Interaction

Moderate: diabetes, liver dysfunction

Volume of Distribution

  • 7 L

Half Life

~6 days

Clearance

  • 36 - 28 mL/h [SC doses ranging from 10 to 20 mg/day]

Innovators Monograph

You find simplified version here SOMAVERT10mgpolvereesolventepersoluzioneiniettabile

*** Taking medicines without doctor's advice can cause long-term problems.
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