Sorbitol
Sorbitol Uses, Dosage, Side Effects, Food Interaction and all others data.
A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
| Trade Name | Sorbitol |
| Availability | Rx and/or OTC |
| Generic | Sorbitol |
| Sorbitol Other Names | D-glucitol, D-Sorbit, D-Sorbitol, G-ol, L-Gulitol, Sorbitol |
| Related Drugs | MiraLAX, Colace, docusate, Linzess, bisacodyl, senna |
| Weight | 70% |
| Type | Oral liquid |
| Formula | C6H14O6 |
| Weight | Average: 182.1718 Monoisotopic: 182.07903818 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Sorbitol is a product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
Used as a non-stimulant laxative via an oral suspension or enema.
Sorbitol is also used to associated treatment for these conditions: Constipation, Constipation caused by Pregnancy, Occasional Constipation, Bladder irrigation therapy, Bowel preparation therapy, Preparation for rectoscopic or sigmoidoscopic examination
How Sorbitol works
Sorbitol exerts its laxative effect by drawing water into the large intestine, thereby stimulating bowel movements.
Toxicity
Acute oral toxicity (LD50): 15900 mg/kg [Rat].
Food Interaction
No interactions found.Sorbitol Disease Interaction
Major: inflammatory bowel disease, intestinal obstruction disorders, fluid expansionModerate: diabetes, sodium imbalances
Elimination Route
Sorbitol will either be excreted in the urine by the kidneys, or metabolized to carbon dioxide and dextrose.
Innovators Monograph
You find simplified version here Sorbitol
