Spasmine SR
Spasmine SR Uses, Dosage, Side Effects, Food Interaction and all others data.
Spasmine SR is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating Irritable Bowel Syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping to restore the normal movement of the gut.
| Trade Name | Spasmine SR |
| Generic | Mebeverine |
| Mebeverine Other Names | Mebeverina, Mebeverine, Mebeverinum |
| Type | |
| Formula | C25H35NO5 |
| Weight | Average: 429.557 Monoisotopic: 429.251523231 |
| Groups | Approved, Investigational |
| Therapeutic Class | Anticholinergics |
| Manufacturer | |
| Available Country | Lebanon |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the symptomatic treatment of Irritable Bowel Syndrome (IBS) and other conditions include:
- Chronic irritable colon
- Spastic constipation
- Mucous colitis
- Colicky abdominal pain
- Persistent non-specific diarrhea
Spasmine SR is also used to associated treatment for these conditions: Abdominal Pain, Abdominal Spasms, Abnormal Bowel Movement Such as Constipation, Diarrhea, Abdominal Pain, Irritable Bowel Syndrome (IBS), Bowel discomfort
Dosage
Spasmine SR dosage
135 mg tid, may reduce gradually after several wk when the desired effect has been obtained; 100 mg tid has also been used. As modified-release cap: 200 mg bid.
Spasmine SR is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.
Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.
Side Effects
Generally Spasmine SR is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.
Precaution
Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Spasmine SR does not excrete in the breast milk after administering the therapeutic dose.
Special Warning
Use in children: Spasmine SR is not recommended in children under 10 years.
Acute Overdose
Symptoms: CNS excitability
Management: Symptomatic and supportive treatment. Gastric lavage may be considered in case of multiple intoxication or if discovered w/in approx 1 hr.
Storage Condition
Store below 30° C.
Innovators Monograph
You find simplified version here Spasmine SR
Spasmine SR contains Mebeverine see full prescribing information from innovator Spasmine SR Monograph, Spasmine SR MSDS, Spasmine SR FDA label
FAQ
What is Spasmine SR used for?
Spasmine SR helps with muscle spasms. It can be used to ease painful stomach cramps if you have irritable bowel syndrome (IBS) or other conditions.
How safe is Spasmine SR?
Spasmine SR is generally safe and you're unlikely to have side effects. Some people may get an itchy rash (hives).
How does Spasmine SR work?
Spasmine SR works by relaxing the muscles in your intestine. This relieves the cramps and pain that can be caused by IBS or other conditions.
What are the common side effects of Spasmine SR?
The common side effects of Spasmine SR are:
- Nausea.
- Vomiting.
- Rash.
- Headache.
- Heartburn.
- Indigestion.
- Constipation.
- Dizziness.
Is Spasmine SR safe during pregnancy?
Spasmine SR are not recommended during pregnancy.
Is Spasmine SR safe during breastfeeding?
It is usually safe to breastfeed while taking Spasmine SR. Some of the medicine may pass into your breast milk. However, this is in small amounts and unlikely to harm your baby.
Can I drink alcohol with Spasmine SR?
Yes, you can drink alcohol with Spasmine SR.
When should be best taken of Spasmine SR?
It's best to take your Spasmine SR 20 minutes before a meal.
How often can I take Spasmine SR?
The recommended dose is one tablet three times a day. Do not take more than three tablets per day.
Can I Spasmine SR take on an empty stomach?
Spasmine SR should take on an empty stomach. If you take it twice a day, take it before breakfast and dinner. If you take it 3 times a day, take it before breakfast, lunch and dinner.
How long does Spasmine SR take to work?
Spasmine SR starts to work after 1 hour. You should feel better 1 to 3 hours after taking it.
What is the half life of Spasmine SR?
The steady state elimination half-life of DMAC is 2.45 h.
Does Spasmine SR raise blood pressure?
Spasmine SR also significantly reduced heart rate and arterial blood pressure.
Can I take Spasmine SR for a long time?
You will usually only take Spasmine SR if you are having a flare-up of your IBS symptoms.
Who should not take Spasmine SR?
The recommended dose is one tablet three times a day. Do not take more than three tablets per day. The number of tablets you take may be lowered if your symptoms improve. Children and adolescents: Spasmine SR is not recommended for use in children and adolescents below 18 years of age.
What happen If I missed Spasmine SR?
If you miss a dose of Spasmine SR, skip the missed dose and take the next one as usual. Do not take a double dose to make up for a missed dose. If you forget doses often, it may help to set an alarm to remind you.
What happens if I take too much Spasmine SR?
If you take too much Spasmine SR by accident, it is unlikely to harm you. Speak to a pharmacist or doctor if you're worried.
Can I just stop taking Spasmine SR?
You can stop taking Spasmine SR when you feel better. This may take up to 2 weeks. If you do not get better within 2 weeks of taking Spasmine SR, or get worse at any time, talk to a doctor.
Does Spasmine SR raise blood pressure?
Spasmine SR also significantly reduced heart rate and arterial blood pressure.
Does Spasmine SR cause tachycardia?
Transient bradycardia followed by tachycardia.
