SSR-126517E

SSR-126517E Uses, Dosage, Side Effects, Food Interaction and all others data.

SSR-126517E is a second generation synthetic pentasaccharide that binds antithrombin with such high affinity that it assumes a plasma half-life of 80 hours.

Table Of contents

• SSR-126517E
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	SSR-126517E
Generic	SSR-126517E
Type
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Investigated for use/treatment in thrombosis and venous thromboembolism.

How SSR-126517E works

SSR126517E is a biotinylated form of idraparinux. It can be neutralized with intravenous recombinant avidin. Avidin binds biotinylated fondaparinux with high affinity, and the complex is then rapidly cleared.

SSR126517E also has an advantage over idraparinux in that an antidote is available when rapid reversal is required. None of the new agents has a specific antidote except SSR126517E. The lack of an antidote in other anticoagulants agents has been a major cause for the development of SSR126517E.

Innovators Monograph

You find simplified version here SSR-126517E