Suconal Cream 1%
Suconal Cream 1% Uses, Dosage, Side Effects, Food Interaction and all others data.
Suconal Cream 1% interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Suconal Cream 1% may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.
Suconal Cream 1% is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Suconal Cream 1% exhibits fungicidal activity in vitro against Candida albicans, other species of the genus Candida, and against Torulopsis glabrata. Suconal Cream 1% prevents the growth and function of some fungal organisms by interfering with the production of substances needed to preserve the cell membrane. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
| Trade Name | Suconal Cream 1% |
| Generic | Tioconazole |
| Tioconazole Other Names | Tioconazol, Tioconazole, Tioconazolum |
| Weight | 1% |
| Type | Cream |
| Formula | C16H13Cl3N2OS |
| Weight | Average: 387.711 Monoisotopic: 385.981416859 |
| Groups | Approved |
| Therapeutic Class | Drugs used in Vaginal and Vulval condition, Topical Antifungal preparations |
| Manufacturer | Supreme Pharmaceutical Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
Suconal Cream 1% is used for the local treatment of vulvovaginal candidiasis (moniliasis). As Suconal Cream 1% has been shown to be effective only for candidal vulvovaginitis, the diagnosis should be confirmed by KOH smears and/or cultures. Other pathogens commonly associated with vulvovaginitis should be ruled out by appropriate methods.
Studies have shown that women taking oral contraceptives have a cure rate similar to those not taking such agents when treated with Suconal Cream 1%.
Suconal Cream 1% is also used to associated treatment for these conditions: Fungal skin infection, Infection Mixed, Onychomycosis, Skin Infections, Bacterial, Vaginal Candidiasis, Vulvovaginal Candidiasis, Cutaneous dermatophyte infection, Superficial Fungal skin infection
How Suconal Cream 1% works
Suconal Cream 1% interacts with 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Suconal Cream 1% may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.
Dosage
Suconal Cream 1% dosage
Topical: Apply & massage gently into the affected & surrounding skin area once or twice a day. In intertriginous areas, apply sparingly & smoothed in well to avoid macerating effects. Duration: 1-6 weeks.
Vaginal candidiasis:
- Adult: As 6.5% ointment: Admin intravaginally at bedtime as a single dose.
- Child: ≥12 yr Admin at bedtime as a single dose.
Side Effects
Occasional local transient & mild irritation; if hypersensitivity reaction develop, treatment should be discontinued & appropriate therapy should be instituted.
Toxicity
Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.
Precaution
Not for ophthalmic use.
Food Interaction
No interactions found.Elimination Route
Systemic absorption following a single intravaginal application of tioconazole in nonpregnant patients is negligible.
Pregnancy & Breastfeeding use
Pregnancy Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Contraindication
Suconal Cream 1% is contraindicated in individuals who have been shown to be sensitive to imidazole antifungal agents or to other components of the ointment.
Special Warning
Safety and effectiveness in pregnant and diabetic patients have not been established
Innovators Monograph
You find simplified version here Suconal Cream 1%
Suconal Cream 1% contains Tioconazole see full prescribing information from innovator Suconal Cream 1% Monograph, Suconal Cream 1% MSDS, Suconal Cream 1% FDA label
FAQ
What is Suconal Cream 1% used for?
Suconal Cream 1% is an antifungal medicine. It is used to treat yeast infections of the vagina.
How safe is Suconal Cream 1%?
Both open and controlled clinical trials have clearly demonstrated the efficacy and safety of topical preparations of Suconal Cream 1% for treating superficial dermatophyte or yeast infections of the skin and vaginal candidiasis.
What is the common side effects of Suconal Cream 1%?
Common side effects may include:
- vaginal redness or swelling;
- mild stomach pain;
- pain or burning when you urinate;
- headache, runny or stuffy nose; or.
- mild vaginal burning, itching or irritation after use.
Is Suconal Cream 1% safe during pregnancy?
There are no controlled data in human pregnancy. Even though systemic absorption is insignificant, the manufacturer considers use of the topical solution contraindicated during pregnancy due to the prolonged duration of therapy.
Is Suconal Cream 1% safe during breastfeeding?
Breastfeeding is not recommended during use of this drug. An alternative agent may be preferred, especially while breastfeeding newborn or preterm infants; the manufacturer recommends nursing women consult a healthcare provider before use of this drug
How long does it take for Suconal Cream 1% to work?
Suconal Cream 1% starts working within 5 to 10 hours after being inserted into the vagina. You may see improvement in symptoms within 1 or 2 days after starting this medication.
How do you get Suconal Cream 1% out of your vagina?
First sit over the toilet and try to push as much of the Suconal Cream 1% out of your vagina as possible using your vaginal canal muscles. Also lightly wipe up as much of the serum you can with toilet paper, just dab it. Then run a warm bath. Sit in the water and try to flush a much of the ointment out as possible.
How should I use Suconal Cream 1% vaginal?
Do not take Suconal Cream 1% vaginal by mouth. It is for use only in your vagina.You should only use this treatment three to four times. If it isn't effective at treating the infection after four applications, see your doctor.
What happens if I overdose?
Since Suconal Cream 1% vaginal is used as a single dose from a prefilled applicator, an overdose is unlikely to occur.
What should I avoid while using Suconal Cream 1% vaginal?
Avoid wearing tight-fitting, synthetic clothing such as nylon underwear or panty hose that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.
How long is too long to treat a yeast infection?
More severe yeast infections could take up to 2 weeks to clear without treatment. If your infection is causing painful and uncomfortable symptoms for more than 3 days, you should seek medical treatment.
How many times can I take yeast infection Suconal Cream 1%?
You should only use this treatment three to four times. If it isn't effective at treating the infection after four applications, see your doctor.
What happen if I stop Suconal Cream 1% suddenly ?
Skipping doses may also increase your risk of further infection that is resistant.
