Sucralose
Sucralose Uses, Dosage, Side Effects, Food Interaction and all others data.
Sucralose is an artificial sweetener and sugar substitute. The majority of ingested sucralose is not broken down by the body, so it is noncaloric. In the European Union, it is also known under the E number E955. Sucralose is about 320 to 1,000 times sweeter than sucrose, three times as sweet as aspartame, twice as sweet as saccharin and three times as sweet as acesulfame potassium. It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a longer shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste, stability, and safety.
| Trade Name | Sucralose |
| Generic | Sucralose |
| Sucralose Other Names | Sucralose, Trichlorosucrose |
| Type | |
| Formula | C12H19Cl3O8 |
| Weight | Average: 397.63 Monoisotopic: 396.0145507 |
| Groups | Experimental |
| Therapeutic Class | Oral nutritional preparations |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Sucralose is used in many food and beverage products because it is a no-calorie sweetener, does not promote dental cavities, is safe for consumption by diabetics and nondiabetics, and does not affect insulin levels,although the powdered form of sucralose-based sweetener product Splenda (as most other powdered sucralose products) contains 95% (by volume) bulking agents dextrose and maltodextrin that do affect insulin levels. Sucralose is used as a replacement for, or in combination with, other artificial or natural sweeteners such as aspartame, acesulfame potassium or high-fructose corn syrup. Sucralose is used in products such as candy, breakfast bars and soft drinks.
Sucralose is also used to associated treatment for these conditions: Healthy Normal Weight
Dosage
Sucralose dosage
The acceptable daily intake of sucralose is 5-15 mg/kg body weight. Normally 1 tablet (8 mg) in a cup of tea or coffee is enough to sweeten the drink.
Side Effects
No known side effects
Interaction
There are no known drug interactions and none well documented.
Pregnancy & Breastfeeding use
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Contraindication
No known contraindication.
Innovators Monograph
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FAQ
What is Sucralose used for?
Sucralose is a general used sweetener that can be found in a variety of foods including baked goods, beverages, chewing gum, gelatins, and frozen dairy desserts. It is heat stable, meaning that it stays sweet even when used at high temperatures during baking, making it suitable as a sugar substitute in baked goods.
How safe is Sucralose?
Sucralose is generally recognized as safe .That means that experts consider the substance in question safe based on available research.
What are the common side effects of Sucralose?
- alters glucose and insulin levels
- increases risk of digestive problems
- alters gut health and damages the GI tract
- kills probiotics
- may play a role in certain cancers
- generates toxic compounds when heated
- may lead to weight gain
The common side effects of Sucralose are include:
Is Sucralose safe to consume everyday?
Research into sweeteners shows they're perfectly safe to eat or drink on a daily basis as part of a healthy diet.
Is Sucralose safe during pregnancy?
Sucralose is safe to use during pregnancy as it does not cross the placenta.
Is Sucralose safe during breastfeeding?
The sweeteners Sucralose are found in breastmilk after maternal ingestion, at variable levels considered safe.
Can I drink alcohol with Sucralose?
Alcohol may hit the bloodstream faster when mixed with artificially sweetened beverages, compared with those containing sugar.
Is Sucralose bad for your liver?
Histopathological examination inSucralose and stevia administrated groups confirmed the biochemical results; where it revealed a severe damage in liver and kidney sections.
Can diabetics have Sucralose?
Artificial sweeteners like Sucralose are marketed as sugar substitutes that don't raise blood sugar levels, making them a safer choice for diabetics.
How much Sucralose is safe per day?
Acceptable Daily Intake 5 milligrams for each kilogram of body weight. For a 150-pound person, 340 milligrams a day would be safe.
Does Sucralose build up in my body?
Passes through the body undigested and builds up in fat cells.
Does Sucralose raise triglycerides?
The administration of Sucralose reduces the level of triglycerides, while elevates the level of total cholesterol, HDL-C and LDL-C, when compared to control rats.
Does Sucralose make me hungry?
The artificial sweetener may actually increase appetite in women and people with obesity.
Is Sucralose really bad for me?
Yet scientists haven't found any direct negative health effects in people who consume Sucralose long-term. That's true both for healthy people and those with diabetes. While Sucralose may cause problems at higher doses, most people consume nowhere near that amount.
Will Sucralose affect my fertility?
Artificial sweeteners as like Sucralose found in soft drinks may reduce female fertility, a study suggests.
Do Sucralose affect sperm?
Diet drinks: research shows that aspartame is linked with lower sperm count and can contribute to sperm DNA damage.
Are Sucralose hard on the kidneys?
At the present time current research does not indicate artificial sweeteners are harmful for patients with chronic kidney disease.
Can Sucralose be broken down in the body?
Sucralose is an artificial sweetener and sugar substitute. The majority of ingested Sucralose is not broken down by the body, so it is noncaloric.
Is Sucralose bad for my gut?
In particular, previous studies have shown that Sucralose consumption can alter the gut microbiota. The gut microbiome plays a key role in processes related to host health, such as food digestion and fermentation, immune cell development, and enteric nervous system regulation.
Is Sucralose bad for teeth?
Sucralose has no effect on tooth decay.
