Sulfuno
Sulfuno Uses, Dosage, Side Effects, Food Interaction and all others data.
Sulfuno is an antibacterial in the sulfonamide class.
Sulfuno is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Trade Name | Sulfuno |
Generic | Sulfamoxole |
Sulfamoxole Other Names | 2-(p-Aminobenzolsulfonamido)-4,5-dimethyloxazol, Oxasulfa, Sulfadimethyloxazole, Sulfamoxol, Sulfamoxole, Sulfamoxolum, Sulphamoxole |
Type | Tablet |
Formula | C11H13N3O3S |
Weight | Average: 267.304 Monoisotopic: 267.067761987 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | Zydus Cadila Healthcare Ltd |
Available Country | India, |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of bacterial infection.
How Sulfuno works
Sulfuno is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme is needed for the proper processing of para-aminobenzoic acid (PABA) which is essential for folic acid synthesis. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
Toxicity
Oral Rat LD50: > 12500 mg/kg; Intravenous Mouse LD50: 1 g/kg
Innovators Monograph
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