Sutilains

Sutilains Uses, Dosage, Side Effects, Food Interaction and all others data.

Sutilains is a member of the keratase family which includes agents such as papain. It is able to dissolve the intercellular matrix which helps with desquamation. Sutilains contains proteolytic enzymes derived from Bacillus subtilis and it is available as a cream-colored odorless powder. One gram of sutilain powder contains 250,000 casein units of proteolytic activity. Sutilains was developed by Abbott and FDA approved on June 12, 1969. It is currently discontinued.

Reports indicated that sutilain exhibited a rapid and effective debridement when used for the treatment of burns, decubiti and traumatic wounds. In the case of peripheral vascular ulcerations, it did not respond in a predictable manner. When used, sutilain caused a rapid dissolution of the surface of the treated skin zone. However, a graftable wound bed as achieved no more rapidly than if saline soaks had been used since the enzyme appears to be ineffective in removing deep dermal elements and necrotic fat.

Sutilains
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Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
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Trade Name	Sutilains
Generic	Sutilain
Sutilain Other Names	Sutilaina, Sutilaines, Sutilains
Type
Protein binding	This pharmacokinetic parameter is not relevant.
Groups	Approved, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Sutilains was indicated, in the form of an ointment, as a biochemical debridement of second and third-degree burns, incisional traumatic and pyrogenic wounds and ulcers occurring due to peripheral vascular diseases.

Sutilains is also used to associated treatment for these conditions: Debridement of necrotic tissue