taflotan multi
taflotan multi Uses, Dosage, Side Effects, Food Interaction and all others data.
taflotan multi, a prostaglandin analog is a selective FP prostanoid receptor agonist which is believed to reduce intraocular pressure by increasing uveoscleral outflow of aqueous humor.
taflotan multi is a novel prostaglandin analog with a high affinity for the fluoroprostaglandin (FP) receptor PGF2α. taflotan multi has an affinity for the FP receptor that is approximately 12 times higher than that of the carboxylic acid of latanoprost, but with almost no potential to bind to other receptors.
| Trade Name | taflotan multi |
| Generic | Tafluprost |
| Tafluprost Other Names | Tafluprost |
| Type | |
| Formula | C25H34F2O5 |
| Weight | Average: 452.5313 Monoisotopic: 452.237430608 |
| Groups | Approved |
| Therapeutic Class | Drugs for miotics and glaucoma |
| Manufacturer | |
| Available Country | Russia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
taflotan multi is used for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
taflotan multi is also used to associated treatment for these conditions: Increased Intra Ocular Pressure (IOP), Ocular Hypertension
How taflotan multi works
taflotan multi acid is a prostanoid selective FP receptor agonist that is believed to reduce the intraocular pressure (IOP) by increasing the outflow of aqueous humor. Studies in animals and humans suggest that the main mechanism of action is increased uveoscleral outflow.
Dosage
taflotan multi dosage
Instill one drop in the affected eye(s) once daily in the evening.
Side Effects
The most frequently reported treatment-related side effect is ocular hyperemia. Rare side effects observed include eye irritation and blurred vision.
Toxicity
Most common ocular adverse reaction is conjunctival hyperemia (range 4% – 20%).
Precaution
- For ophthalmic use only.
- To avoid possible contamination of the drops, do not touch the dropper tip or to any surface.
- Should be used with caution in patients with active intraocular inflammation (e.g., iritis/uveitis).
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least five (5) minutes between applications.
Food Interaction
No interactions found.Volume of Distribution
The highest concentration of tafluprost acid was found in the cornea and conjunctiva.
Elimination Route
Following instillation, tafluprost is absorbed through the cornea and is hydrolyzed to the biologically active acid metabolite, tafluprost acid. taflotan multi is an ester which makes the drug lipophillic enough to be quickly absorbed through. When administered to the eye, the peak plasma concentration (Cmax) and time to peak plasma concentration (Tmax) of tafluprost acid in healthy subjects was 26 pg/mL and 10 minutes respectively. a AUC, tafluprost acid = 394 pgmin/mL - 432 pgmin/mL.
Elimination Route
Mean plasma tafluprost acid concentrations were below the limit of quantification of the bioanalytical assay (10 pg/mL) at 30 minutes following topical ocular administration of tafluprost 0.0015% ophthalmic solution. In male rats, it was observed that tafluprost was excreted into the feces.
Pregnancy & Breastfeeding use
Use in pregnancy: Pregnancy category C. There are no adequate and well-controlled studies in pregnant women. taflotan multi ophthalmic solution should be used during pregnancy unless the potential benefit justifies the potential risk to the fetus.
Use in lactation: It is not known whether taflotan multi is excreted in human milk. Caution should be exercised while giving this ophthalmic solution to a nursing mother.
Contraindication
taflotan multi ophthalmic solution is contraindicated in patients who are hypersensitive to any component of this product.
Special Warning
Use in children: Use in pediatric patients is not recommended.
Use in elderly patients: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
Innovators Monograph
You find simplified version here taflotan multi
taflotan multi contains Tafluprost see full prescribing information from innovator taflotan multi Monograph, taflotan multi MSDS, taflotan multi FDA label
FAQ
What is taflotan multi used for?
taflotan multi ophthalmic is used to treat glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision) and ocular hypertension (a condition which causes increased pressure in the eye).
What are the side effects of taflotan multi eye drops?
Side Effects:
- Blurred vision.
- burning, dry, or itching eyes.
- decreased vision.
- eye discharge or excessive tearing.
- eye pain.
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid.
How taflotan multi works?
taflotan multi is in a class of medications called prostaglandin analogs.taflotan multi works lowers pressure in the eye by increasing the flow of natural eye fluids out of the eye.It is in a class of medications called prostaglandin analogs.
Is safe taflotan multi during pregnancy?
This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Is taflotan multi safe during breasfeeding?
taflotan multi is not likely to reach the breastmilk or bloodstream of the infant or to cause any adverse effects in breastfed infants. Professional guidelines consider prostaglandin eye drops acceptable during breastfeeding.
How do you use taflotan multi?
taflotan multi is usually instilled in the affected eye(s) once a day in the evening. Use taflotan multi at around the same time in the evening every day.
What are the indications of taflotan multi?
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
How can I use of taflotan multi?
Your eye doctor will tell you how much of taflotan multi to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
How long does it take taflotan multi to work?
taflotan multi takes about 2 to 4 hours to kick in and 12 hours to reach maximum effect.
Should taflotan multi be refrigerated?
After opening the foil pouch, refrigeration is not required.
Does taflotan multi make eyelashes grow?
taflotan multi can make you grow more eyelashes or cause your current eyelashes to become longer and thicker.
