Taro-Amcinonide

Taro-Amcinonide Uses, Dosage, Side Effects, Food Interaction and all others data.

Taro-Amcinonide is a corticosteroid.

Taro-Amcinonide is a topical corticosteroid. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Taro-Amcinonide reduces or inhibits the actions of chemicals in the body that cause inflammation, redness, and swelling. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man. When in an ointment form, amcinonide also helps the skin maintain moisture.

Taro-Amcinonide
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Taro-Amcinonide
Availability	Prescription only
Generic	Amcinonide
Amcinonide Other Names	Amcinónida, Amcinonide, Amcinonidum, Triamcinolonacetatcyclopentanonid
Related Drugs	Humira, Cosentyx, Dupixent, prednisone, methotrexate, Remicade, Stelara, cyclosporine, infliximab, Temovate
Type
Formula	C₂₈H₃₅FO₇
Weight	Average: 502.5717 Monoisotopic: 502.236681679
Groups	Approved
Therapeutic Class
Manufacturer
Available Country	Canada, United States
Last Updated:	September 19, 2023 at 7:00 am

Uses

Taro-Amcinonide is a topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.

For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Taro-Amcinonide is also used to associated treatment for these conditions: Inflammation, Pruritus

How Taro-Amcinonide works

The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Taro-Amcinonide has affinity for the glucocorticoid receptor. It has weak affinity for the progesterone receptor, and virtually no affinity for the mineralocorticoid, estrogen, or androgen receptors.

Toxicity

Results from acute toxicity studies do not indicate that any risk of acute intoxication is to be expected following a single dermal application of an overdose (application over a large area under conditions favorable to absorption) or inadvertent oral ingestion.

Food Interaction

No interactions found.

Taro-Amcinonide Disease Interaction

Moderate: diabetes, diaper rash, hyperadrenocorticism, infections, ocular toxicities

Elimination Route

Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption.

Elimination Route

Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.