Tavan-SP
Tavan-SP Uses, Dosage, Side Effects, Food Interaction and all others data.
Tavan-SP is a sulfated pentosyl polysaccharide with heparin-like properties.
Tavan-SP sodium is a low molecular weight heparin-like compound. It has anticoagulant and fibrinolytic effects.
| Trade Name | Tavan-SP |
| Generic | Pentosan polysulfate |
| Pentosan polysulfate Other Names | Pentosan polysulfate, Pentosan sulfuric polyester, Pentosane polysulfate, Pentosani polysulfas, Pentosano polisulfato, Pentosanpolysulfat |
| Type | |
| Formula | C10H18O21S4 |
| Weight | Average: 602.497 Monoisotopic: 601.922340398 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Tavan-SP is a sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
For the relief of bladder pain or discomfort associated with interstitial cystitis.
Tavan-SP is also used to associated treatment for these conditions: Cystitis interstitial
How Tavan-SP works
Tavan-SP is a polymer of xylose hydrogen sulfate and contains two sulfate groups per carbohydrate monomer. It binds Fibroblast growth factors (FGFs) as well as other heparin-binding growth factors. It has been shown to interact also with the heparin-binding site of FGFR-1. It inhibits the growth of SW13 adrenocortical cells transfected with FGF-4 and tumorigenicity of MCF-7 breast carcinoma cells transfected with FGF-1 or FGF-4.
Food Interaction
- Avoid herbs and supplements with anticoagulant/antiplatelet activity. Taking pentosan polysulfate with anticoagulant herbs may increase bleeding risk, which is an adverse effect of pentosan polysulfate.
- Take on an empty stomach. Take at least 1 hour before or 2 hours after meals.
Elimination Route
Slow
Half Life
4.8 hours
Innovators Monograph
You find simplified version here Tavan-SP
