Tavegyl Children

Tavegyl Children Uses, Dosage, Side Effects, Food Interaction and all others data.

An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.

Tavegyl Children is an antihistamine that also induces anticholinergic and sedative effects. Antihistamines competitively antagonize various physiological effects of histamine including increased capillary permeability and dilatation, the formation of edema, the "flare" and "itch" response, and gastrointestinal and respiratory smooth muscle constriction. Within the vascular tree, H1- receptor antagonists inhibit both the vasoconstrictor and vasodilator effects of histamine. Depending on the dose, H1- receptor antagonists can produce CNS stimulation or depression. Most antihistamines exhibit central and/or peripheral anticholinergic activity. Antihistamines act by competitively blocking H1- receptor sites. Antihistamines do not pharmacologically antagonize or chemically inactivate histamine, nor do they prevent the release of histamine.

Tavegyl Children
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Tavegyl Children
Availability	Rx and/or OTC
Generic	Clemastine
Clemastine Other Names	Clemastina, Clemastine, Clemastinum
Related Drugs	prednisone, cetirizine, loratadine, fluticasone nasal, promethazine, diphenhydramine, triamcinolone, Benadryl, Zyrtec, Xolair
Weight	0.1mg
Type	Syrup
Formula	C₂₁H₂₆ClNO
Weight	Average: 343.89 Monoisotopic: 343.170292166
Groups	Approved, Investigational
Therapeutic Class
Manufacturer	Novartis India Ltd
Available Country	India
Last Updated:	September 19, 2023 at 7:00 am

Uses

Tavegyl Children is an antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.

For the relief of symptoms associated with allergic rhinitis such as sneezing, rhinorrhea, pruritus and acrimation. Also for the management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Used as self-medication for temporary relief of symptoms associated with the common cold.

Tavegyl Children is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Angioedema, Common Cold, Urticaria

How Tavegyl Children works

Tavegyl Children is a selective histamine H1 antagonist and binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

Toxicity

Oral LD₅₀ in rat and mouse is 3550 mg/kg and 730 mg/kg, respectively. Antihistamine overdosage reactions may vary from central nervous system depression to stimulation. In children, stimulation predominates initially in a syndrome which may include excitement, hallucinations, ataxia, incoordination, muscle twitching, athetosis, hyperthermia, cyanosis convulsions, tremors, and hyperreflexia followed by postictal depression and cardio-respiratory arrest. Convulsions in children may be preceded by mild depression. Dry mouth, fixed dilated pupils, flushing of the face, and fever are common. In adults, CNS depression, ranging from drowsiness to coma, is more common.

Food Interaction

Avoid alcohol.
Take with food.

[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.

Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.