Tetramide
Tetramide Uses, Dosage, Side Effects, Food Interaction and all others data.
A tetracyclic compound with antidepressant effects. Tetramide was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Tetramide is a tetracyclic antidepressant that has antihistaminic and hypnosedative, but almost no anticholinergic, effect. It is a weak inhibitor of norepinephrine reuptake and strongly stimulates the release of norepinephrine. Interactions with serotonin receptors in the central nervous system have also been found. Its effect is usually noticeable after one to three weeks. Tetramide may cause drowsiness and hematological problems.
| Trade Name | Tetramide |
| Generic | Mianserin |
| Mianserin Other Names | Mianserin, Mianserina, Mianserine, Miansérine, Mianserinum, Mianseryna |
| Type | |
| Formula | C18H20N2 |
| Weight | Average: 264.3648 Monoisotopic: 264.16264865 |
| Protein binding | 90% |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Japan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Tetramide is a tetracyclic antidepressant with therapeutic activity similar to amitriptyline used to treat depression and anxiety.
For the treatment of depression.
Tetramide is also used to associated treatment for these conditions: Depression
How Tetramide works
Tetramide's mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
Toxicity
Oral rat LD50: 780mg/kg
Elimination Route
Absorbed following oral administration.
Half Life
10-17 hours
Innovators Monograph
You find simplified version here Tetramide
