Thyrotropic Releasing Hormone

Thyrotropic Releasing Hormone Uses, Dosage, Side Effects, Food Interaction and all others data.

Thyrotropic Releasing Hormone is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.

Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary hypothyroidism and acromegaly.

Trade Name Thyrotropic Releasing Hormone
Availability Discontinued
Generic Protirelin
Protirelin Other Names Protirelin, Protirelina, Thyroliberin, Thyrotropic releasing hormone, Thyrotropic-releasing factor, Thyrotropin releasing hormone, Thyrotropin-releasing factor, TSH-releasing factor, TSH-releasing hormone
Type
Formula C16H22N6O4
Weight Average: 362.3837
Monoisotopic: 362.170253222
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Thyrotropic Releasing Hormone
Thyrotropic Releasing Hormone

Uses

Thyrotropic Releasing Hormone is a synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland.

Food Interaction

  • Do not take with or immediately after a high-fat meal. Fatty food can disrupt the TSH assay by increasing lipid levels in the blood.
  • Take with or without food. Take protirelin either after a low-fat meal or on an empty stomach.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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