Timonate
Timonate Uses, Dosage, Side Effects, Food Interaction and all others data.
Tiemonium are quaternary ammonium antimuscarinic agent with peripheral effect similar to those of atropine. Tiemonium strengthens calcium bonding with phospholipids and proteins thus stabilizing the cell membrane of the GI tract.
Trade Name | Timonate |
Generic | Tiemonium Methylsulphate |
Weight | 50mg, 5mg/2ml |
Type | Tablet, Im/iv Injection |
Therapeutic Class | Anticholinergics |
Manufacturer | Pacific Pharmaceuticals Ltd |
Available Country | Bangladesh |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Timonate is an antispasmodic drug. It reduces muscle spasms of the intestine, biliary system, uterus & urinary bladder. It is used for the pain in gastrointestinal, biliary, urinary and gynecological disease such as gastroenteritis, diarrhea, dysentery, biliary colic, enterocolitis, cholecystytis, colonopathies, mild cystitis, & spasmodic dysmenorrhoea.
Dosage
Timonate dosage
Tablet: Recommended oral dose of Timonate tablet is 2-6 tablets (100-300 mg) daily in divided dose.
Injection: Recommended injectable dose is 1 Timonate Injection 3 times daily, through Intravenous route slowly or Intramuscular route.
Syrup:
- Children: 3 mg to 6 mg/kg/day or 1.5 ml to 3 ml/kg/day in 3 divided doses.
- Adult: 30 mg to 90 mg or 15 ml to 45 ml 3 times daily or as directed by physician.
Suppository: Recommended dose is 20 mg Timonate suppository two or three times daily, through rectal route.
Side Effects
Side effect with the use of Timonate is very rare.
Precaution
Precautions should be exercised for treatment of patients with disorders of prostate, chronic bronchitis, coronary insufficiency, ambient hyperthermia, cardiac disorders, thyroid disorders, serious renal & hepatic insufficiency.
Interaction
Timonate should not be used with other drugs without prior consult of a registered physician to avoid possible drug interaction.
Pregnancy & Breastfeeding use
Timonate may be used in pregnancy only if it is clearly needed by the assessment of risk benefit ratio. Timonate may be used in lactating mother only if it is clearly needed by the assessment of risk benefit ratio.
Contraindication
Timonate should not be used in Glucoma or where acute pain of eyeball with vision disturbance was found. This drug should also not be used in patients with the disorder of prostate or urinary bladder.
Special Warning
Paediatric use: safety and effectiveness of Tiemonium methylsulphate in paediatric patients have not been established.
Geriatric use: Efficacy and safety were maintained with increasing age.
Acute Overdose
Occasional retention of urine may occur in case of overdoses.
Storage Condition
Keep it in a cool and dry place, protected from light and moisture. Keep all medicines away from the reach of the children.
Innovators Monograph
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FAQ
What is Timonate used for?
Timonate is an antispasmodic drug. It used to reduces muscle spasms of the intestine, biliary system, uterus & urinary bladder.
What are the side effects of Timonate?
Timonate may have some undesirable effects in certain individuals like risk of hypotension and tachycardia if ingested in high doses rapidly.
Is Timonate safe during pregnancy?
Timonate is not recommended during pregnancy.
Is Timonate safe during breastfeeding?
Timonate is not recommended during breastfeeding.Please discuss the risks and benefits with your doctor.
Can I drink alcohol with Timonate?
Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Timonate.
Can I drive after taking Timonate?
If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Timonate medicine then it may not be safe to drive a vehicle or operate heavy machinery.
When should not to use Timonate?
Hypersensitivity to Timonate is a contraindication. In addition,Timonate should not be used if you have the following conditions:
angle closure glaucoma,
urethro prostatic disorder.
How can used Timonate?
Timonate usual dose is 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses.
Can I overdose on Timonate?
Occasional retention of urine may occur in case of overdoses.
How does Timonate work?
Timonate prevents the effects of acetylcholine by blocking its binding to muscarinic cholinergic receptors at neuroeffector sites on smooth muscle of GI tract 2, regardless of their function and innervations.