Tolflex

Tolflex Uses, Dosage, Side Effects, Food Interaction and all others data.

Tolflex is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels

Trade Name Tolflex
Generic Tolperisone
Tolperisone Other Names Tolperisone
Type Tablet
Formula C16H23NO
Weight Average: 245.366
Monoisotopic: 245.177964365
Groups Investigational
Therapeutic Class Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants
Manufacturer Merck Limited
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Tolflex
Tolflex

Uses

Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.

Tolflex Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain

Tolflex is also used to associated treatment for these conditions: Spasticity

Dosage

Tolflex dosage

Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.

Children:

  • 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
  • 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses

Side Effects

Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.

Precaution

In case of children, the prescribed dose and duration of treatment should closely be observed.

Interaction

Concomitant use of Methocarbamol with Tolflex Hydrochloride has been reported to cause disturbance of visual accommodation.

Pregnancy & Breastfeeding use

Tolflex Hydrochloride should be used in pregnancy according to physician's advice. Tolflex hydrochloride should not be used during breast-feeding.

Contraindication

Hypersensitivity, Myasthenia Gravis and nursing mother.

Acute Overdose

Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.

Storage Condition

Tolflex Hydrochloride should be stored below 30° C. Keep out of reach of children

Innovators Monograph

You find simplified version here Tolflex

Tolflex contains Tolperisone see full prescribing information from innovator Tolflex Monograph, Tolflex MSDS, Tolflex FDA label

FAQ

What is Tolflex used for?

Tolflex is a muscle relaxant used to relieve spasticity after stroke in adults.Tolflex is an oral, centrally acting muscle relaxant.

How safe is Tolflex?

Tolflex hydrochloride represents an effective and safe treatment of central post stroke spasticity, neurolathyrism, and painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants.

What are the common side effects of Tolflex?

The common side effects of Tolflex are include: tiredness, dizziness, nausea, mouth dryness, increase in liver enzymes. Contraindications: myasthenia gravis, pregnancy, breast feeding.

Is Tolflex safe during pregnancy?

Tolflex should be avoided, particularly during the first trimester of pregnancy to avoid embryo toxicity.

Is Tolflex safe during breastfeeding?

This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.

Can I drink alcohol with Tolflex?

Tolflex is not sedating and does not interact with alcohol.

How long does Tolflex take to work?

Tolflex is absorbed nearly completely from the gut and reaches its peak blood plasma concentration after 1.5 hours.

Is Tolflex a sedative?

Tolflex does not cause any sedation and does not impair reaction times.

How do you take Tolflex?

Take Tolflex with food.Take it with or after food or a glass of milk. Do not take in larger amounts than advised/prescribed.

Does Tolflex cause drowsiness?

The most common adverse effects were asthenia and sleepiness(drowsiness).

When should not I take Tolflex?

This medicine is not recommended for use in patients with a known allergy to Tolflex or any other inactive ingredient present along with it.

What happens if I miss a dose?

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose.

What happens if I overdose?

Seek emergency medical treatment or contact the doctor in case of an overdose.

*** Taking medicines without doctor's advice can cause long-term problems.
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