Tolifast Sr

Uses

Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.

Tolifast Sr Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain

Tolifast Sr is also used to associated treatment for these conditions: Spasticity

Dosage

Tolifast Sr dosage

Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.

Children:

• 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
• 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses

Side Effects

Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.

Precaution

In case of children, the prescribed dose and duration of treatment should closely be observed.

Interaction

Concomitant use of Methocarbamol with Tolifast Sr Hydrochloride has been reported to cause disturbance of visual accommodation.

Pregnancy & Breastfeeding use

Tolifast Sr Hydrochloride should be used in pregnancy according to physician's advice. Tolifast Sr hydrochloride should not be used during breast-feeding.

Contraindication

Hypersensitivity, Myasthenia Gravis and nursing mother.

Acute Overdose

Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.

Storage Condition

Tolifast Sr Hydrochloride should be stored below 30° C. Keep out of reach of children

Innovators Monograph

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