Толизор
Толизор Uses, Dosage, Side Effects, Food Interaction and all others data.
Толизор is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels
| Trade Name | Толизор |
| Generic | Tolperisone |
| Tolperisone Other Names | Tolperisone |
| Type | |
| Formula | C16H23NO |
| Weight | Average: 245.366 Monoisotopic: 245.177964365 |
| Groups | Investigational |
| Therapeutic Class | Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants |
| Manufacturer | |
| Available Country | Russia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.
Толизор Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain
Толизор is also used to associated treatment for these conditions: Spasticity
Dosage
Толизор dosage
Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.
Children:
- 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
- 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses
Side Effects
Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.
Precaution
In case of children, the prescribed dose and duration of treatment should closely be observed.
Interaction
Concomitant use of Methocarbamol with Толизор Hydrochloride has been reported to cause disturbance of visual accommodation.
Pregnancy & Breastfeeding use
Толизор Hydrochloride should be used in pregnancy according to physician's advice. Толизор hydrochloride should not be used during breast-feeding.
Contraindication
Hypersensitivity, Myasthenia Gravis and nursing mother.
Acute Overdose
Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.
Storage Condition
Толизор Hydrochloride should be stored below 30° C. Keep out of reach of children
Innovators Monograph
You find simplified version here Толизор
Толизор contains Tolperisone see full prescribing information from innovator Толизор Monograph, Толизор MSDS, Толизор FDA label
FAQ
What is Толизор used for?
Толизор is a muscle relaxant used to relieve spasticity after stroke in adults.Толизор is an oral, centrally acting muscle relaxant.
How safe is Толизор?
Толизор hydrochloride represents an effective and safe treatment of central post stroke spasticity, neurolathyrism, and painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants.
What are the common side effects of Толизор?
The common side effects of Толизор are include: tiredness, dizziness, nausea, mouth dryness, increase in liver enzymes. Contraindications: myasthenia gravis, pregnancy, breast feeding.
Is Толизор safe during pregnancy?
Толизор should be avoided, particularly during the first trimester of pregnancy to avoid embryo toxicity.
Is Толизор safe during breastfeeding?
This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.
Can I drink alcohol with Толизор?
Толизор is not sedating and does not interact with alcohol.
How long does Толизор take to work?
Толизор is absorbed nearly completely from the gut and reaches its peak blood plasma concentration after 1.5 hours.
Is Толизор a sedative?
Толизор does not cause any sedation and does not impair reaction times.
How do you take Толизор?
Take Толизор with food.Take it with or after food or a glass of milk. Do not take in larger amounts than advised/prescribed.
Does Толизор cause drowsiness?
The most common adverse effects were asthenia and sleepiness(drowsiness).
When should not I take Толизор?
This medicine is not recommended for use in patients with a known allergy to Толизор or any other inactive ingredient present along with it.
What happens if I miss a dose?
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose.
What happens if I overdose?
Seek emergency medical treatment or contact the doctor in case of an overdose.
