Tolperison HEXAL
Tolperison HEXAL Uses, Dosage, Side Effects, Food Interaction and all others data.
Tolperison HEXAL is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels
| Trade Name | Tolperison HEXAL |
| Generic | Tolperisone |
| Tolperisone Other Names | Tolperisone |
| Type | |
| Formula | C16H23NO |
| Weight | Average: 245.366 Monoisotopic: 245.177964365 |
| Groups | Investigational |
| Therapeutic Class | Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants |
| Manufacturer | |
| Available Country | Germany |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.
Tolperison HEXAL Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain
Tolperison HEXAL is also used to associated treatment for these conditions: Spasticity
Dosage
Tolperison HEXAL dosage
Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.
Children:
- 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
- 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses
Side Effects
Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.
Precaution
In case of children, the prescribed dose and duration of treatment should closely be observed.
Interaction
Concomitant use of Methocarbamol with Tolperison HEXAL Hydrochloride has been reported to cause disturbance of visual accommodation.
Pregnancy & Breastfeeding use
Tolperison HEXAL Hydrochloride should be used in pregnancy according to physician's advice. Tolperison HEXAL hydrochloride should not be used during breast-feeding.
Contraindication
Hypersensitivity, Myasthenia Gravis and nursing mother.
Acute Overdose
Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.
Storage Condition
Tolperison HEXAL Hydrochloride should be stored below 30° C. Keep out of reach of children
Innovators Monograph
You find simplified version here Tolperison HEXAL
Tolperison HEXAL contains Tolperisone see full prescribing information from innovator Tolperison HEXAL Monograph, Tolperison HEXAL MSDS, Tolperison HEXAL FDA label
FAQ
What is Tolperison HEXAL used for?
Tolperison HEXAL is a muscle relaxant used to relieve spasticity after stroke in adults.Tolperison HEXAL is an oral, centrally acting muscle relaxant.
How safe is Tolperison HEXAL?
Tolperison HEXAL hydrochloride represents an effective and safe treatment of central post stroke spasticity, neurolathyrism, and painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants.
What are the common side effects of Tolperison HEXAL?
The common side effects of Tolperison HEXAL are include: tiredness, dizziness, nausea, mouth dryness, increase in liver enzymes. Contraindications: myasthenia gravis, pregnancy, breast feeding.
Is Tolperison HEXAL safe during pregnancy?
Tolperison HEXAL should be avoided, particularly during the first trimester of pregnancy to avoid embryo toxicity.
Is Tolperison HEXAL safe during breastfeeding?
This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.
Can I drink alcohol with Tolperison HEXAL?
Tolperison HEXAL is not sedating and does not interact with alcohol.
How long does Tolperison HEXAL take to work?
Tolperison HEXAL is absorbed nearly completely from the gut and reaches its peak blood plasma concentration after 1.5 hours.
Is Tolperison HEXAL a sedative?
Tolperison HEXAL does not cause any sedation and does not impair reaction times.
How do you take Tolperison HEXAL?
Take Tolperison HEXAL with food.Take it with or after food or a glass of milk. Do not take in larger amounts than advised/prescribed.
Does Tolperison HEXAL cause drowsiness?
The most common adverse effects were asthenia and sleepiness(drowsiness).
When should not I take Tolperison HEXAL?
This medicine is not recommended for use in patients with a known allergy to Tolperison HEXAL or any other inactive ingredient present along with it.
What happens if I miss a dose?
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose.
What happens if I overdose?
Seek emergency medical treatment or contact the doctor in case of an overdose.
