Toluifera Pereirae Wood Oil
Toluifera Pereirae Wood Oil Uses, Dosage, Side Effects, Food Interaction and all others data.
Toluifera Pereirae Wood Oil is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and Benzyl benzoate. Toluifera Pereirae Wood Oil has also presented several allergens such as cinnamic acid, Benzyl alcohol and Vanillic acid. Under the FDA, balsam of Peru is considered as an inactive ingredient to be used for approved drug products as well as an approved food additive under the categorization of generally recognized as safe (GRAS). By Health Canada, the balsam of Peru is approved by the use of over-the-counter combination products and it is currently approved in veterinary products. By the EMA, the balsam of Peru is approved and categorized under the herbal medicine products.
As a parasiticide, balsam of Peru is believed to destroy the itch acarus and its eggs. As an expectorant, it is reported that its administration produces a reduction in mucous secretions. As a heart stimulant, it has been reported to locally increase the blood flow to even 45% at about 3 hours post administration. The antiseptic effect was demonstrated in vitro against gram-positive and gram-negative bacteria as well as against fungi. In skin ulcers, the balsam of Peru was shown to accelerate repair and differentiation of scar tissue.
| Trade Name | Toluifera Pereirae Wood Oil |
| Generic | Balsam of Peru |
| Balsam of Peru Other Names | Balsam (peru) oil, Balsam of Peru essential oil, Balsam Peru, Balsam Peru oil, Balsam peru volatile oil, Balsam-of-peru oil, bálsamo de Perú, bálsamo Perú, China oil, Myrospermum pereirae wood oil, Myrospermum sonsonatense wood oil, Myroxylon pereirae wood oil, Peru balsam oil, Peruvian balsam oil, Toluifera pereirae wood oil |
| Type | |
| Protein binding | This pharmacokinetic property has not been determined. |
| Groups | Nutraceutical, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Toluifera Pereirae Wood Oil is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies.
As a medical agent, balsam of Peru is used in the local treatment of burns and wounds as an antiseptic. It is also used as an expectorant, heart stimulant to increase blood pressure and as a parasiticide.
Toluifera Pereirae Wood Oil is also used to associated treatment for these conditions: Acne, Decubitus Ulcer, Dermatitis, Diaper Rash, Hemorrhoids, Incision of the Sclerosed Anorectal Vein, Incision of the Thrombosed Anorectal Vein, Open Wound, Proctitis, Rash, Skin Infections, Venous Stasis Ulcers (VSU), Cryptitis, Pustules, Postoperative treatment, Preoperative medication
How Toluifera Pereirae Wood Oil works
Toluifera Pereirae Wood Oil is a capillary bed stimulant that increases circulation in the wound area and it also acts as a mild bactericidal. When balsam of Peru is administered in mucous tissues is profused and it lessens the secretions.
Toxicity
Reports have indicated contact urticaria in users that present some sort of contact with balsam of Peru. The reported LD50 in the rabbit is 2-5 g/kg.
Volume of Distribution
This pharmacokinetic property has not been determined.
Elimination Route
When administered dermally, absorption is not expected. When applied topically, the balsam of Peru was detectable in the skin after 1 hour but no longer after 8 hours. The absorption is significantly increased in occluded skin and it is moderately irritating.
Half Life
This pharmacokinetic property has not been determined.
Clearance
This pharmacokinetic property has not been determined.
Elimination Route
As balsam of Peru is rapidly metabolized to form hippuric acid it is rapidly excreted via the kidneys and about 75-80% of the dose is eliminated 6 hours after oral administration.
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