Topifuran 0.2%

Topifuran 0.2% Uses, Dosage, Side Effects, Food Interaction and all others data.

A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections. Nitrofurazone has also been administered orally in the treatment of trypanosomiasis.

Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.

Topifuran 0.2%
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Topifuran 0.2%
Generic	Nitrofural
Nitrofural Other Names	Furacilin, Nitrofural
Type
Formula	C₆H₆N₄O₄
Weight	Average: 198.1362 Monoisotopic: 198.0389047
Groups	Approved, Investigational, Vet approved
Therapeutic Class
Manufacturer
Available Country	Egypt
Last Updated:	September 19, 2023 at 7:00 am

Uses

Topifuran 0.2% is a topical antibacterial for the prevention and treatment of bacterial infections of the skin.

For the treatment of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.

Topifuran 0.2% is also used to associated treatment for these conditions: Skin Infections

How Topifuran 0.2% works

The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of glucose and pyruvate. This activity is believed also to affect pyruvate dehydrogenase, citrate synthetase, malate dehydrogenase, glutathione reductase, and pyruvate decarboxylase.