Torcetrapib
Torcetrapib Uses, Dosage, Side Effects, Food Interaction and all others data.
Torcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin and the study drug.
Trade Name | Torcetrapib |
Generic | Torcetrapib |
Torcetrapib Other Names | Torcetrapib |
Type | |
Formula | C26H25F9N2O4 |
Weight | Average: 600.4733 Monoisotopic: 600.167061143 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in peripheral vascular disease and hyperlipidemia.
How Torcetrapib works
Torcetrapib is an inhibitor of cholesteryl ester-transfer protein (CETP) that increases high-density lipoprotein (HDL) cholesterol levels. The drug increases HDL-cholesterol and apolipoprotein A-I levels and decreases LDL-cholesterol and apolipoprotein B levels. The effect is showed in monotherapy and when administered in combination with statins.
Innovators Monograph
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