Torcetrapib

Torcetrapib Uses, Dosage, Side Effects, Food Interaction and all others data.

Torcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin and the study drug.

Trade Name Torcetrapib
Generic Torcetrapib
Torcetrapib Other Names Torcetrapib
Type
Formula C26H25F9N2O4
Weight Average: 600.4733
Monoisotopic: 600.167061143
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Torcetrapib
Torcetrapib

Uses

Investigated for use/treatment in peripheral vascular disease and hyperlipidemia.

How Torcetrapib works

Torcetrapib is an inhibitor of cholesteryl ester-transfer protein (CETP) that increases high-density lipoprotein (HDL) cholesterol levels. The drug increases HDL-cholesterol and apolipoprotein A-I levels and decreases LDL-cholesterol and apolipoprotein B levels. The effect is showed in monotherapy and when administered in combination with statins.

Innovators Monograph

You find simplified version here Torcetrapib

*** Taking medicines without doctor's advice can cause long-term problems.
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