Tripélennamine
Tripélennamine Uses, Dosage, Side Effects, Food Interaction and all others data.
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripélennamine is administered by various routes, including topically.
Used to treat the effects of colds and allergies. Tripélennamine is an antihistamine. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Tripélennamine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Trade Name | Tripélennamine |
Availability | Discontinued |
Generic | Tripelennamine |
Tripelennamine Other Names | Tripelennamin, Tripelennamina, Tripélennamine, Tripelennamine, Tripelennaminum |
Related Drugs | hydroxyzine, loratadine, levocetirizine, Vistaril, Atarax, Xyzal |
Type | |
Formula | C16H21N3 |
Weight | Average: 255.358 Monoisotopic: 255.173547687 |
Groups | Approved, Vet approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Tripélennamine is a histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.
Used for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.
Tripélennamine is also used to associated treatment for these conditions: Itching caused by Insect Bites, Itching caused by Jellyfish Stings, Itching caused by Nettles
How Tripélennamine works
Tripélennamine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.
Toxicity
Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands and trouble in sleeping.
Food Interaction
No interactions found.[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.
Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.
Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
Tripélennamine Drug Interaction
Unknown: carvedilol, levothyroxine, estradiol, metronidazole topical, clopidogrel, ergocalciferol, cholecalciferol
Tripélennamine Disease Interaction
Moderate: anticholinergic effects, asthma/COPD, cardiovascular, renal/liver disease
Elimination Route
Well absorbed in the digestive tract.
Innovators Monograph
You find simplified version here Tripélennamine