Troleandomycin

Troleandomycin Uses, Dosage, Side Effects, Food Interaction and all others data.

A macrolide antibiotic that is similar to erythromycin.

Troleandomycin, like other macrolide antibiotics, inhibits bacterial protein synthesis to prevent growth.

Trade Name Troleandomycin
Availability Discontinued
Generic Troleandomycin
Troleandomycin Other Names Oleandocetine, Oleandomycin triacetate, Oleandomycin triacetyl ester, Triacetyloleandomycin, Triacetyloleandomycinum, Tribiocillina, Troleandomicina, Troleandomycin, Troleandomycine
Related Drugs amoxicillin, doxycycline, ciprofloxacin, metronidazole, azithromycin, clindamycin, levofloxacin, Levaquin, penicillin v potassium, Bicillin L-A
Type
Formula C41H67NO15
Weight Average: 813.9684
Monoisotopic: 813.451070479
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Troleandomycin
Troleandomycin

Uses

For the treatment of bacterial infection.

How Troleandomycin works

As a macrolide, troleandomycin binds to the 50S subunit of the bacterial ribosome . This binding inhibits translocation of tRNA along the A, P, and E sites of the ribosome. With tRNA unable to move from site to site, amino acids cannot be deposited onto the polypeptide chain leading to failure of protein synthesis. Bacterial cell growth and duplication is inhibited without the ability to generate the necessary proteins.

Toxicity

Troleandomycin inhibits clearance of theophylline and can increase the likelyhood of toxicity in patients recieving theophylline therapy .

Troleandomycin Disease Interaction

Major: colitis, QT prolongation, liver disease

Innovators Monograph

You find simplified version here Troleandomycin

*** Taking medicines without doctor's advice can cause long-term problems.
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