Tropinium Methobromide Mandelate

Tropinium Methobromide Mandelate Uses, Dosage, Side Effects, Food Interaction and all others data.

Tropinium Methobromide Mandelate is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.

Tropinium Methobromide Mandelate belongs to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.

Tropinium Methobromide Mandelate
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Tropinium Methobromide Mandelate
Generic	Homatropine methylbromide
Homatropine methylbromide Other Names	Homatropine methylbromide, Homatropini methylbromidum, Méthylbromure d'homatropine, Methylhomatropine, Methylhomatropine bromide, Methylhomatropinum bromatum, Metilbromuro de homatropina, Omatropina metilbromuro, Tropinium methobromide mandelate
Type
Formula	C₁₇H₂₄BrNO₃
Weight	Average: 370.281 Monoisotopic: 369.093956286
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Tropinium Methobromide Mandelate is a muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.

Used in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcers, gastric ulcers and duodenal ulcers, to reduce further gastric acid secretion and delay gastric emptying.

Tropinium Methobromide Mandelate is also used to associated treatment for these conditions: Cough

How Tropinium Methobromide Mandelate works

Homatropine is a quaternary ammonium muscarinic acetylcholine receptor antagonist. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Tropinium Methobromide Mandelate inhibits the muscarinic actions of acetylcholine on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These postganglionic receptor sites are present in the autonomic effector cells of the smooth muscle, cardiac muscle, sinoatrial and atrioventricular nodes, and exocrine glands. Depending on the dose, anticholinergics may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and gallbladder.