Trypsinum crystallisatum
Trypsinum crystallisatum Uses, Dosage, Side Effects, Food Interaction and all others data.
Trypsinum crystallisatum is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine. Trypsinum crystallisatum contains a nucleophilic residue Ser in the enzyme active site which attacks the carbonyl moiety of the substrate peptide bond to form an acyl-enzyme intermediate . This nucleophilic attack is facilitated by the catalytic triad consisting of histidine-57, aspartate-102, and serine-195. Trypsinum crystallisatum also contains an oxyanion hole that stabilizes the charge negative charge on the carbonyl oxygen atom formed from the cleavage of peptide bonds. Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is intended to aid in digestion when administered orally.
| Trade Name | Trypsinum crystallisatum |
| Generic | Trypsin |
| Trypsin Other Names | Tripsina, Trypsin |
| Type | |
| Groups | Approved, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Russia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Trypsinum crystallisatum is a naturally occurring proteolytic enzyme found in the digestive tract of mammals. Used clinically in combination with bromelain and rutosides in the treatment of some inflammatory conditions.
Trypsinum crystallisatum is also used to associated treatment for these conditions: Inflammatory Reaction of the genitourinary tract, Osteoarthritis (OA), Thrombophlebitis, Traumatic Injuries, Localized soft tissue rheumatism
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